Molecular cloning of a human gene that regulates chromosome condensation and is essential for cell proliferation.

Por Kai, R, Ohtsubo, M, Sekiguchi, M, Nishimoto, T
Publicado em 1986

Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene.

Por Uchida, S, Sekiguchi, T, Nishitani, H, Miyauchi, K, Ohtsubo, M, Nishimoto, T
Publicado em 1990

The yeast SRM1 protein and human RCC1 protein share analogous functions.

Por Clark, K L, Ohtsubo, M, Nishimoto, T, Goebl, M, Sprague, G F
Publicado em 1991

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition.

Por Ohtsubo, M, Theodoras, A M, Schumacher, J, Roberts, J M, Pagano, M
Publicado em 1995

Metabolic abnormality of calf skeletal muscle is improved by localised muscle training without changes in blood flow in chronic heart failure

Por Ohtsubo, M., Yonezawa, K., Nishijima, H., Okita, K., Hanada, A., Kohya, T., Murakami, T., Kitabatake, A.
Publicado em 1997

Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells.

Por Yamashita, K, Yasuda, H, Pines, J, Yasumoto, K, Nishitani, H, Ohtsubo, M, Hunter, T, Sugimura, T, Nishimoto, T
Publicado em 1990

Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S.cerevisiae.

Por Ohtsubo, M, Yoshida, T, Seino, H, Nishitani, H, Clark, K L, Sprague, G F, Frasch, M, Nishimoto, T
Publicado em 1991

Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis.

Por Nishitani, H, Ohtsubo, M, Yamashita, K, Iida, H, Pines, J, Yasudo, H, Shibata, Y, Hunter, T, Nishimoto, T
Publicado em 1991

Dissociation between muscle metabolism and oxygen kinetics during recovery from exercise in patients with chronic heart failure

Por Hanada, A, Okita, K, Yonezawa, K, Ohtsubo, M, Kohya, T, Murakami, T, Nishijima, H, Tamura, M, Kitabatake, A
Publicado em 2000