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Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene.

At the nonpermissive temperature, premature chromosome condensation (PCC) occurs in tsBN2 cells derived from the BHK cell line, which can be converted to the Ts+ phenotype by the human RCC1 gene. To prove that the RCC1 gene is the mutant gene in tsBN2 cells, which have RCC1 mRNA and protein of the s...

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Detalhes bibliográficos
Main Authors: Uchida, S, Sekiguchi, T, Nishitani, H, Miyauchi, K, Ohtsubo, M, Nishimoto, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC360843/
https://ncbi.nlm.nih.gov/pubmed/2300055
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