Epigallocatechin activates haem oxygenase-1 expression via protein kinase Cδ and Nrf2

Por Ogborne, Richard M., Rushworth, Stuart A., O’Connell, Maria A.
Publicado em 2008

Identification of Small‐Molecule Inhibitors of the Antiapoptotic Protein Myeloid Cell Leukaemia‐1 (Mcl‐1)

Por Beekman, Andrew M., O'Connell, Maria A., Howell, Lesley A.
Publicado no ChemMedChem (2015)

Lipopolysaccharide-induced expression of NAD(P)H:quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes

Por Rushworth, Stuart A., MacEwan, David J., O’Connell, Maria A.
Publicado em 2008

Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction

Por Steel, Richard, Cowan, Jonathan, Payerne, Estelle, O'Connell, Maria A., Searcey, Mark
Publicado em 2012

Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells

Por Warner, Emily F., Rodriguez-Ramiro, Ildefonso, O’Connell, Maria A., Kay, Colin D.
Publicado no Molecules (2018)

Intake of B vitamins in childhood and adult life in relation to psychological distress among women in a British birth cohort

Por Mishra, Gita D, McNaughton, Sarah A, O’Connell, Maria A, Prynne, Celia J, Kuh, Diana
Publicado em 2008

Common Phenolic Metabolites of Flavonoids, but Not Their Unmetabolized Precursors, Reduce the Secretion of Vascular Cellular Adhesion Molecules by Human Endothelial Cells(1)(2)(3)

Por Warner, Emily F, Zhang, Qingzhi, Raheem, K Saki, O’Hagan, David, O’Connell, Maria A, Kay, Colin D
Publicado no J Nutr (2016)

Identification of selective protein–protein interaction inhibitors using efficient in silico peptide-directed ligand design

Por Beekman, Andrew M., Cominetti, Marco M. D., Walpole, Samuel J., Prabhu, Saurabh, O'Connell, Maria A., Angulo, Jesus, Searcey, Mark
Publicado no Chem Sci (2019)

Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells

Por Warner, Emily F., Smith, Michael J., Zhang, Qingzhi, Raheem, K. Saki, O'Hagan, David, O'Connell, Maria A., Kay, Colin D.
Publicado no Mol Nutr Food Res (2017)

Flavonoid metabolites reduce tumor necrosis factor‐α secretion to a greater extent than their precursor compounds in human THP‐1 monocytes

Por di Gesso, Jessica L., Kerr, Jason S., Zhang, Qingzhi, Raheem, Saki, Yalamanchili, Sai Krishna, O'Hagan, David, Kay, Colin D., O'Connell, Maria A.
Publicado no Mol Nutr Food Res (2015)

Cytotoxicity of Pyrazine-Based Cyclometalated (C^N(pz)^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties

Por Bertrand, Benoît, Fernandez-Cestau, Julio, Angulo, Jesus, Cominetti, Marco M. D., Waller, Zoë A. E., Searcey, Mark, O’Connell, Maria A., Bochmann, Manfred
Publicado no Inorg Chem (2017)

Seasonal Childhood Anaemia in West Africa Is Associated with the Haptoglobin 2-2 Genotype

Por Atkinson, Sarah H, Rockett, Kirk, Sirugo, Giorgio, Bejon, Philip A, Fulford, Anthony, O'Connell, Maria A, Bailey, Robin, Kwiatkowski, Dominic P, Prentice, Andrew M
Publicado em 2006

Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children

Por Atkinson, Sarah H., Rockett, Kirk A., Morgan, Gareth, Bejon, Philip A., Sirugo, Giorgio, O'Connell, Maria A., Hanchard, Neil, Kwiatkowski, Dominic P., Prentice, Andrew M.
Publicado em 2008

A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules

Por Reed, James, Stephenson, Michael J., Miettinen, Karel, Brouwer, Bastiaan, Leveau, Aymeric, Brett, Paul, Goss, Rebecca J.M., Goossens, Alain, O’Connell, Maria A., Osbourn, Anne
Publicado no Metab Eng (2017)