A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules

Por Reed, James, Stephenson, Michael J., Miettinen, Karel, Brouwer, Bastiaan, Leveau, Aymeric, Brett, Paul, Goss, Rebecca J.M., Goossens, Alain, O’Connell, Maria A., Osbourn, Anne
Publicado no Metab Eng (2017)

The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis

Por Miettinen, Karel, Pollier, Jacob, Buyst, Dieter, Arendt, Philipp, Csuk, René, Sommerwerk, Sven, Moses, Tessa, Mertens, Jan, Sonawane, Prashant D, Pauwels, Laurens, Aharoni, Asaph, Martins, José, Nelson, David R., Goossens, Alain
Publicado no Nat Commun (2017)

The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus

Por Van Moerkercke, Alex, Steensma, Priscille, Schweizer, Fabian, Pollier, Jacob, Gariboldi, Ivo, Payne, Richard, Vanden Bossche, Robin, Miettinen, Karel, Espoz, Javiera, Purnama, Purin Candra, Kellner, Franziska, Seppänen-Laakso, Tuulikki, O’Connor, Sarah E., Rischer, Heiko, Memelink, Johan, Goossens, Alain
Publicado no Proc Natl Acad Sci U S A (2015)

The seco-iridoid pathway from Catharanthus roseus

Por Miettinen, Karel, Dong, Lemeng, Navrot, Nicolas, Schneider, Thomas, Burlat, Vincent, Pollier, Jacob, Woittiez, Lotte, van der Krol, Sander, Lugan, Raphaël, Ilc, Tina, Verpoorte, Robert, Oksman-Caldentey, Kirsi-Marja, Martinoia, Enrico, Bouwmeester, Harro, Goossens, Alain, Memelink, Johan, Werck-Reichhart, Danièle
Publicado em 2014