Selective Radical Trifluoromethylation of Native Residues in Proteins

par Imiołek, Mateusz, Karunanithy, Gogulan, Ng, Wai-Lung, Baldwin, Andrew J., Gouverneur, Véronique, Davis, Benjamin G.
Publié dans J Am Chem Soc (2018)

Nucleic Acid-Based Technologies Targeting Coronaviruses

par Le, Thi Khanh, Paris, Clément, Khan, Khadija Shahed, Robson, Fran, Ng, Wai-Lung, Rocchi, Palma
Publié dans Trends Biochem Sci (2021)

Residue-Selective Protein C-Formylation via Sequential Difluoroalkylation-Hydrolysis

par Imiołek, Mateusz, Isenegger, Patrick G., Ng, Wai-Lung, Khan, Aziz, Gouverneur, Véronique, Davis, Benjamin G.
Publié dans ACS Cent Sci (2021)

Coronavirus RNA Proofreading: Molecular Basis and Therapeutic Targeting

par Robson, Fran, Khan, Khadija Shahed, Le, Thi Khanh, Paris, Clément, Demirbag, Sinem, Barfuss, Peter, Rocchi, Palma, Ng, Wai-Lung
Publié dans Mol Cell (2020)

Coronavirus RNA Proofreading: Molecular Basis and Therapeutic Targeting

par Robson, Fran, Khan, Khadija Shahed, Le, Thi Khanh, Paris, Clément, Demirbag, Sinem, Barfuss, Peter, Rocchi, Palma, Ng, Wai-Lung
Publié dans Mol Cell (2020)

Concise and Stereodivergent Synthesis of Carbasugars Reveals Unexpected Structure-Activity Relationship (SAR) of SGLT2 Inhibition

par Ng, Wai-Lung, Li, Ho-Chuen, Lau, Kit-Man, Chan, Anthony K. N., Lau, Clara Bik-San, Shing, Tony K. M.
Publié dans Sci Rep (2017)

Rationalisation and Validation of an Acrylamide-Free Procedure in Three-Dimensional Histological Imaging

par Lai, Hei Ming, Liu, Alan King Lun, Ng, Wai-Lung, DeFelice, John, Lee, Wing Sang, Li, Heng, Li, Wen, Ng, Ho Man, Chang, Raymond Chuen-Chung, Lin, Bin, Wu, Wutian, Gentleman, Steve M.
Publié dans PLoS One (2016)

Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection

par Mukherjee, Rukmini, Bhattacharya, Anshu, Bojkova, Denisa, Mehdipour, Ahmad Reza, Shin, Donghyuk, Khan, Khadija Shahed, Hei-Yin Cheung, Hayley, Wong, Kam-Bo, Ng, Wai-Lung, Cinatl, Jindrich, Geurink, Paul P., van der Heden van Noort, Gerbrand J., Rajalingam, Krishnaraj, Ciesek, Sandra, Hummer, Gerhard, Dikic, Ivan
Publié dans J Biol Chem (2021)

Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain

par Zhao, Lei, Li, Zhongqi, Vong, Joaquim S. L., Chen, Xinyi, Lai, Hei-Ming, Yan, Leo Y. C., Huang, Junzhe, Sy, Samuel K. H., Tian, Xiaoyu, Huang, Yu, Chan, Ho Yin Edwin, So, Hon-Cheong, Ng, Wai-Lung, Tang, Yamei, Lin, Wei-Jye, Mok, Vincent C. T., Ko, Ho
Publié dans Nat Commun (2020)

In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma

par Li, Fei, Huang, Qingyuan, Luster, Troy A., Hu, Hai, Zhang, Hua, Ng, Wai-Lung, Khodadadi-Jamayran, Alireza, Wang, Wei, Chen, Ting, Deng, Jiehui, Ranieri, Michela, Fang, Zhaoyuan, Pyon, Val, Dowling, Catríona M., Bagdatlioglu, Ece, Almonte, Christina, Labbe, Kristen, Silver, Heather, Rabin, Alexandra R., Jani, Kandarp, Tsirigos, Aristotelis, Papagiannakopoulos, Thales, Hammerman, Peter S., Velcheti, Vamsidhar, Freeman, Gordon J., Qi, Jun, Miller, George, Wong, Kwok-Kin
Publié dans Cancer Discov (2019)

Epigenetic CRISPR screens identify Npm1 as a therapeutic vulnerability in non-small cell lung cancer

par Li, Fei, Ng, Wai-Lung, Luster, Troy A., Hu, Hai, Sviderskiy, Vladislav O., Dowling, Catríona M., Hollinshead, Kate E.R., Zouitine, Paula, Zhang, Hua, Huang, Qingyuan, Ranieri, Michela, Wang, Wei, Fang, Zhaoyuan, Chen, Ting, Deng, Jiehui, Zhao, Kai, So, Hon-Cheong, Khodadadi-Jamayran, Alireza, Xu, Mousheng, Karatza, Angeliki, Pyon, Val, Li, Shuai, Pan, Yuanwang, Labbe, Kristen, Almonte, Christina, Poirier, John T., Miller, George, Possemato, Richard, Qi, Jun, Wong, Kwok-Kin
Publié dans Cancer Res (2020)

Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir

par Lo, Ho Sing, Hui, Kenrie Pui Yan, Lai, Hei-Ming, He, Xu, Khan, Khadija Shahed, Kaur, Simranjeet, Huang, Junzhe, Li, Zhongqi, Chan, Anthony K. N., Cheung, Hayley Hei-Yin, Ng, Ka-Chun, Ho, John Chi Wang, Chen, Yu Wai, Ma, Bowen, Cheung, Peter Man-Hin, Shin, Donghyuk, Wang, Kaidao, Lee, Meng-Hsuan, Selisko, Barbara, Eydoux, Cecilia, Guillemot, Jean-Claude, Canard, Bruno, Wu, Kuen-Phon, Liang, Po-Huang, Dikic, Ivan, Zuo, Zhong, Chan, Francis K. L., Hui, David S. C., Mok, Vincent C. T., Wong, Kam-Bo, Mok, Chris Ka Pun, Ko, Ho, Aik, Wei Shen, Chan, Michael Chi Wai, Ng, Wai-Lung
Publié dans ACS Cent Sci (2021)