Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY‐876

door Siebeneicher, Holger, Cleve, Arwed, Rehwinkel, Hartmut, Neuhaus, Roland, Heisler, Iring, Müller, Thomas, Bauser, Marcus, Buchmann, Bernd
Gepubliceerd in ChemMedChem (2016)

Allosteric MEK1/2 Inhibitor Refametinib (BAY 86-9766) in Combination with Sorafenib Exhibits Antitumor Activity in Preclinical Murine and Rat Models of Hepatocellular Carcinoma

door Schmieder, Roberta, Puehler, Florian, Neuhaus, Roland, Kissel, Maria, Adjei, Alex A, Miner, Jeffrey N, Mumberg, Dominik, Ziegelbauer, Karl, Scholz, Arne
Gepubliceerd in 2013

ZK200775: A phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma

door Turski, Lechoslaw, Huth, Andreas, Sheardown, Malcolm, McDonald, Fiona, Neuhaus, Roland, Schneider, Herbert H., Dirnagl, Ulrich, Wiegand, Frank, Jacobsen, Poul, Ottow, Eckhard
Gepubliceerd in 1998

Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death

door Klutzny, Saskia, Lesche, Ralf, Keck, Matthias, Kaulfuss, Stefan, Schlicker, Andreas, Christian, Sven, Sperl, Carolyn, Neuhaus, Roland, Mowat, Jeffrey, Steckel, Michael, Riefke, Björn, Prechtl, Stefan, Parczyk, Karsten, Steigemann, Patrick
Gepubliceerd in Cell Death Dis (2017)

BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients

door Sugawara, Tatsuo, Lejeune, Pascale, Köhr, Silke, Neuhaus, Roland, Faus, Hortensia, Gelato, Kathy A., Busemann, Matthias, Cleve, Arwed, Lücking, Ulrich, von Nussbaum, Franz, Brands, Michael, Mumberg, Dominik, Jung, Klaus, Stephan, Carsten, Haendler, Bernard
Gepubliceerd in Oncotarget (2016)

Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles

door Eaton, John K, Furst, Laura, Ruberto, Richard A, Moosmayer, Dieter, Hilpmann, André, Ryan, Matthew J, Zimmermann, Katja, Cai, Luke L, Niehues, Michael, Badock, Volker, Kramm, Anneke, Chen, Sixun, Hillig, Roman C, Clemons, Paul A, Gradl, Stefan, Montagnon, Claire, Lazarski, Kiel E, Christian, Sven, Bajrami, Besnik, Neuhaus, Roland, Eheim, Ashley L, Viswanathan, Vasanthi S, Schreiber, Stuart L
Gepubliceerd in Nat Chem Biol (2020)