Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY‐876

Por Siebeneicher, Holger, Cleve, Arwed, Rehwinkel, Hartmut, Neuhaus, Roland, Heisler, Iring, Müller, Thomas, Bauser, Marcus, Buchmann, Bernd
Publicado no ChemMedChem (2016)

Allosteric MEK1/2 Inhibitor Refametinib (BAY 86-9766) in Combination with Sorafenib Exhibits Antitumor Activity in Preclinical Murine and Rat Models of Hepatocellular Carcinoma

Por Schmieder, Roberta, Puehler, Florian, Neuhaus, Roland, Kissel, Maria, Adjei, Alex A, Miner, Jeffrey N, Mumberg, Dominik, Ziegelbauer, Karl, Scholz, Arne
Publicado em 2013

ZK200775: A phosphonate quinoxalinedione AMPA antagonist for neuroprotection in stroke and trauma

Por Turski, Lechoslaw, Huth, Andreas, Sheardown, Malcolm, McDonald, Fiona, Neuhaus, Roland, Schneider, Herbert H., Dirnagl, Ulrich, Wiegand, Frank, Jacobsen, Poul, Ottow, Eckhard
Publicado em 1998

Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death

Por Klutzny, Saskia, Lesche, Ralf, Keck, Matthias, Kaulfuss, Stefan, Schlicker, Andreas, Christian, Sven, Sperl, Carolyn, Neuhaus, Roland, Mowat, Jeffrey, Steckel, Michael, Riefke, Björn, Prechtl, Stefan, Parczyk, Karsten, Steigemann, Patrick
Publicado no Cell Death Dis (2017)

BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients

Por Sugawara, Tatsuo, Lejeune, Pascale, Köhr, Silke, Neuhaus, Roland, Faus, Hortensia, Gelato, Kathy A., Busemann, Matthias, Cleve, Arwed, Lücking, Ulrich, von Nussbaum, Franz, Brands, Michael, Mumberg, Dominik, Jung, Klaus, Stephan, Carsten, Haendler, Bernard
Publicado no Oncotarget (2016)

Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles

Por Eaton, John K, Furst, Laura, Ruberto, Richard A, Moosmayer, Dieter, Hilpmann, André, Ryan, Matthew J, Zimmermann, Katja, Cai, Luke L, Niehues, Michael, Badock, Volker, Kramm, Anneke, Chen, Sixun, Hillig, Roman C, Clemons, Paul A, Gradl, Stefan, Montagnon, Claire, Lazarski, Kiel E, Christian, Sven, Bajrami, Besnik, Neuhaus, Roland, Eheim, Ashley L, Viswanathan, Vasanthi S, Schreiber, Stuart L
Publicado no Nat Chem Biol (2020)