Functional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death

Owing to lagging or insufficient neo-angiogenesis, hypoxia is a feature of most solid tumors. Hypoxic tumor regions contribute to resistance against antiproliferative chemotherapeutics, radiotherapy and immunotherapy. Targeting cells in hypoxic tumor areas is therefore an important strategy for canc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Klutzny, Saskia, Lesche, Ralf, Keck, Matthias, Kaulfuss, Stefan, Schlicker, Andreas, Christian, Sven, Sperl, Carolyn, Neuhaus, Roland, Mowat, Jeffrey, Steckel, Michael, Riefke, Björn, Prechtl, Stefan, Parczyk, Karsten, Steigemann, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386533/
https://ncbi.nlm.nih.gov/pubmed/28358364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.130
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados