CLINICAL AND BIOLOGICAL PREDICTORS FOR COGNITIVE FRAILTY: A POPULATION PREDICTIVE MODEL

por Sargent, L, Nalls, M, Amella, E, Hobgood, S, Slattum, P, Singleton, A
Publicado en Innov Aging (2018)

ESTABLISHING BIOLOGICAL PLAUSIBILITY FOR COGNITIVE FRAILTY: SYSTEMATIC REVIEW

por Sargent, L., Starkweather, A., Hobgood, S., Thompson, H., Nalls, M., Singleton, A., Amella, E.J.
Publicado en Innov Aging (2017)

Genome-wide estimate of the heritability of Multiple System Atrophy

por Federoff, M, Price, TR, Sailer, A, Scholz, S, Hernandez, D, Nicolas, A, Singleton, AB, Nalls, M, Houlden, H
Publicado en Parkinsonism Relat Disord (2015)

COMT genotype and cognitive function: An 8-year longitudinal study in white and black elders

por Fiocco, A.J., Lindquist, K., Ferrell, R., Li, R., Simonsick, E.M., Nalls, M., Harris, T.B., Yaffe, K.
Publicado 2010

Extended tracts of homozygosity identify novel candidate genes associated with late onset Alzheimer’s Disease

por Nalls, M. A., Guerreiro, R. J., Simon-Sanchez, J., Bras, J. T., Traynor, B. J., Gibbs, J. R., Launer, L., Hardy, J., Singleton, A. B.
Publicado 2009

Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease

por Bandres-Ciga, S., Saez-Atienzar, S., Kim, J. J., Makarious, M. B., Faghri, F., Diez-Fairen, M., Iwaki, H., Leonard, H., Botia, J., Ryten, M., Hernandez, D., Gibbs, J. R., Ding, J., Gan-Or, Z., Noyce, A., Pihlstrom, L., Torkamani, A., Soltis, A. R., Dalgard, C. L., Scholz, S. W., Traynor, B. J., Ehrlich, D., Scherzer, C. R., Bookman, M., Cookson, M., Blauwendraat, C., Nalls, M. A., Singleton, A. B.
Publicado en Acta Neuropathol (2020)

Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies

por Demirkan, A., Lahti, J., Direk, N., Viktorin, A., Lunetta, K. L., Terracciano, A., Nalls, M. A., Tanaka, T., Hek, K., Fornage, M., Wellmann, J., Cornelis, M. C., Ollila, H. M., Yu, L., Smith, J. A., Pilling, L. C., Isaacs, A., Palotie, A., Zhuang, W. V., Zonderman, A., Faul, J. D., Sutin, A., Meirelles, O., Mulas, A., Hofman, A., Uitterlinden, A., Rivadeneira, F., Perola, M., Zhao, W., Salomaa, V., Yaffe, K., Luik, A. I., Liu, Y., Ding, J., Lichtenstein, P., Landén, M., Widen, E., Weir, D. R., Llewellyn, D. J., Murray, A., Kardia, S. L. R., Eriksson, J. G., Koenen, K., Magnusson, P. K. E., Ferrucci, L., Mosley, T. H., Cucca, F., Oostra, B. A., Bennett, D. A., Paunio, T., Berger, K., Harris, T. B., Pedersen, N. L., Murabito, J. M., Tiemeier, H., van Duijn, C. M., Räikkönen, K.
Publicado en Psychol Med (2016)

Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults

por Zimmermann, E., Ängquist, L. H., Mirza, S. S., Zhao, J. H., Chasman, D. I., Fischer, K., Qi, Q., Smith, A. V., Thinggaard, M., Jarczok, M. N., Nalls, M. A., Trompet, S., Timpson, N. J., Schmidt, B., Jackson, A. U., Lyytikäinen, L. P., Verweij, N., Mueller-Nurasyid, M., Vikström, M., Marques-Vidal, P., Wong, A., Meidtner, K., Middelberg, R. P., Strawbridge, R. J., Christiansen, L., Kyvik, K. O., Hamsten, A., Jääskeläinen, T., Tjønneland, A., Eriksson, J. G., Whitfield, J. B., Boeing, H., Hardy, R., Vollenweider, P., Leander, K., Peters, A., van der Harst, P., Kumari, M., Lehtimäki, T., Meirhaeghe, A., Tuomilehto, J., Jöckel, K.-H., Ben-Shlomo, Y., Sattar, N., Baumeister, S. E., Smith, G. Davey, Casas, J. P., Houston, D. K., März, W., Christensen, K., Gudnason, V., Hu, F. B., Metspalu, A., Ridker, P. M., Wareham, N. J., Loos, R. J. F., Tiemeier, H., Sonestedt, E., Sørensen, T. I. A.
Publicado en Obes Rev (2015)

Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: A genome-wide association study of 13,372 participants

por Deo, R., Nalls, M.A., Avery, C.L., Smith, J.G., Evans, D.S., Keller, M.F., Butler, A.M., Buxbaum, S.G., Li, G., Quibrera, P. Miguel, Smith, E.N., Tanaka, T., Akylbekova, E.L., Alonso, A., Arking, D.E., Benjamin, E.J., Berenson, G.S., Bis, J.C., Chen, L.Y., Chen, W., Cummings, S.R., Ellinor, P.T., Evans, M.K., Ferrucci, L., Fox, E.R., Heckbert, S.R., Heiss, G., Hsueh, W.C., Kerr, K.F., Limacher, M.C., Liu, Y., Lubitz, S.A., Magnani, J.W., Mehra, R., Marcus, G.M., Murray, S.S., Newman, A.B., Njajou, O., North, K.E., Paltoo, D.N., Psaty, B.M., Redline, S.S., Reiner, A.P., Robinson, J.G., Rotter, J.I., Samdarshi, T.E., Schnabel, R.B., Schork, N.J., Singleton, A.B., Siscovick, D., Soliman, E.Z., Sotoodehnia, N., Srinivasan, S.R., Taylor, H.A., Trevisan, M., Zhang, Z., Zonderman, A.B., Newton-Cheh, C., Whitsel, E.A.
Publicado 2012

MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease

por Juge, P.-A., Lee, J.S., Ebstein, E., Furukawa, H., Dobrinskikh, E., Gazal, S., Kannengiesser, C., Ottaviani, S., Oka, S., Tohma, S., Tsuchiya, N., Rojas-Serrano, J., González-Pérez, M.I., Mejía, M., Buendía-Roldán, I., Falfán-Valencia, R., Ambrocio-Ortiz, E., Manali, E., Papiris, S.A., Karageorgas, T., Boumpas, D., Antoniou, K., van Moorsel, C.H.M., van der Vis, J., de Man, Y.A., Grutters, J.C., Wang, Y., Borie, R., Wemeau-Stervinou, L., Wallaert, B., Flipo, R.-M., Nunes, H., Valeyre, D., Saidenberg-Kermanac’h, N., Boissier, M.-C., Marchand-Adam, S., Frazier, A., Richette, P., Allanore, Y., Sibilia, J., Dromer, C., Richez, C., Schaeverbeke, T., Lioté, H., Thabut, G., Nathan, N., Amselem, S., Soubrier, M., Cottin, V., Clément, A., Deane, K., Walts, A.D., Fingerlin, T., Fischer, A., Ryu, J.H., Matteson, E.L., Niewold, T.B., Assayag, D., Gross, A., Wolters, P., Schwarz, M.I., Holers, M., Solomon, J.J., Doyle, T., Rosas, I.O., Blauwendraat, C., Nalls, M.A., Debray, M.-P., Boileau, C., Crestani, B., Schwartz, D.A., Dieudé, P.
Publicado en N Engl J Med (2018)

Genome-wide meta-analyses of smoking behaviors in African Americans

por David, S P, Hamidovic, A, Chen, G K, Bergen, A W, Wessel, J, Kasberger, J L, Brown, W M, Petruzella, S, Thacker, E L, Kim, Y, Nalls, M A, Tranah, G J, Sung, Y J, Ambrosone, C B, Arnett, D, Bandera, E V, Becker, D M, Becker, L, Berndt, S I, Bernstein, L, Blot, W J, Broeckel, U, Buxbaum, S G, Caporaso, N, Casey, G, Chanock, S J, Deming, S L, Diver, W R, Eaton, C B, Evans, D S, Evans, M K, Fornage, M, Franceschini, N, Harris, T B, Henderson, B E, Hernandez, D G, Hitsman, B, Hu, J J, Hunt, S C, Ingles, S A, John, E M, Kittles, R, Kolb, S, Kolonel, L N, Le Marchand, L, Liu, Y, Lohman, K K, McKnight, B, Millikan, R C, Murphy, A, Neslund-Dudas, C, Nyante, S, Press, M, Psaty, B M, Rao, D C, Redline, S, Rodriguez-Gil, J L, Rybicki, B A, Signorello, L B, Singleton, A B, Smoller, J, Snively, B, Spring, B, Stanford, J L, Strom, S S, Swan, G E, Taylor, K D, Thun, M J, Wilson, A F, Witte, J S, Yamamura, Y, Yanek, L R, Yu, K, Zheng, W, Ziegler, R G, Zonderman, A B, Jorgenson, E, Haiman, C A, Furberg, H
Publicado 2012

Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's

por Liu, Ganqiang, Boot, Brendon, Locascio, Joseph J., Jansen, Iris E., Winder‐Rhodes, Sophie, Eberly, Shirley, Elbaz, Alexis, Brice, Alexis, Ravina, Bernard, van Hilten, Jacobus J., Cormier‐Dequaire, Florence, Corvol, Jean‐Christophe, Barker, Roger A., Heutink, Peter, Marinus, Johan, Williams‐Gray, Caroline H., Scherzer, Clemens R., Scherzer, C., Hyman, B.T., Ivinson, A.J., Trisini‐Lipsanopoulos, A., Franco, D., Burke, K., Sudarsky, L.R., Hayes, M.T., Umeh, C.C., Growdon, J.H., Schwarzschild, M.A., Hung, A.Y., Flaherty, A.W., Wills, A.‐M., Mejia, N.I., Gomperts, S.N., Khurana, V., Selkoe, D.J., Yi, T., Page, K., Liao, Z., Barker, R., Foltynie, T., Williams‐Gray, C.H., Mason, S., Winder‐Rhodes, S., Barker, R., Williams‐Gray, C.H., Breen, D., Cummins, G., Evans, J., Winder‐Rhodes, S., Corvol, J.‐C., Brice, A., Elbaz, A., Mallet, A., Vidailhet, M., Bonnet, A.‐M., Bonnet, C., Grabli, D., Hartmann, A., Klebe, S., Lacomblez, L., Mangone, G., Bourdain, F., Brandel, J.‐P., Derkinderen, P., Durif, F., Mesnage, V., Pico, F., Rascol, O., Forlani, S., Lesage, S., Tahiri, K., van Hilten, J.J., Marinus, J., Liao, Z., Page, K., Franco, D., Duong, K., Yi, T., Trisini‐Lipsanopoulos, A., Dong, X., Sudarsky, L.R., Hutten, S.J., Amr, S.S., Shoulson, I., Tanner, C.M., Lang, A.E., Nalls, M.A.
Publicado en Ann Neurol (2016)

GWAS for executive function and processing speed suggests involvement of the CADM2 gene

por Ibrahim-Verbaas, CA, Bressler, J, Debette, S, Schuur, M, Smith, AV, Bis, JC, Davies, G, Trompet, S, Smith, JA, Wolf, C, Chibnik, LB, Liu, Y, Vitart, V, Kirin, M, Petrovic, K, Polasek, O, Zgaga, L, Fawns-Ritchie, C, Hoffmann, P, Karjalainen, J, Lahti, J, Llewellyn, DJ, Schmidt, CO, Mather, KA, Chouraki, V, Sun, Q, Resnick, SM, Rose, LM, Oldmeadow, C, Stewart, M, Smith, BH, Gudnason, V, Yang, Q, Mirza, SS, Jukema, JW, deJager, PL, Harris, TB, Liewald, DC, Amin, N, Coker, LH, Stegle, O, Lopez, OL, Schmidt, R, Teumer, A, Ford, I, Karbalai, N, Becker, JT, Jonsdottir, MK, Au, R, Fehrmann, RSN, Herms, S, Nalls, M, Zhao, W, Turner, ST, Yaffe, K, Lohman, K, van Swieten, JC, Kardia, SLR, Knopman, DS, Meeks, WM, Heiss, G, Holliday, EG, Schofield, PW, Tanaka, T, Stott, DJ, Wang, J, Ridker, P, Gow, AJ, Pattie, A, Starr, JM, Hocking, LJ, Armstrong, NJ, McLachlan, S, Shulman, JM, Pilling, LC, Eiriksdottir, G, Scott, RJ, Kochan, NA, Palotie, A, Hsieh, Y-C, Eriksson, JG, Penman, A, Gottesman, RF, Oostra, BA, Yu, L, DeStefano, AL, Beiser, A, Garcia, M, Rotter, JI, Nöthen, MM, Hofman, A, Slagboom, PE, Westendorp, RGJ, Buckley, BM, Wolf, PA, Uitterlinden, AG, Psaty, BM, Grabe, HJ, Bandinelli, S, Chasman, DI, Grodstein, F, Räikkönen, K, Lambert, J-C, Porteous, DJ, Price, JF, Sachdev, PS, Ferrucci, L, Attia, JR, Rudan, I, Hayward, C, Wright, AF, Wilson, JF, Cichon, S, Franke, L, Schmidt, H, Ding, J, de Craen, AJM, Fornage, M, Bennett, DA, Deary, IJ, Ikram, MA, Launer, LJ, Fitzpatrick, AL, Seshadri, S, van Duijn, CM, Mosley, TH
Publicado en Mol Psychiatry (2015)