GWAS for BMI: a treasure trove of fundamental insights into the genetic basis of obesity

por Speakman, J.R., Loos, R.J.F., O’Rahilly, S., Hirschhorn, J.N., Allison, D.B.
Publicado en Int J Obes (Lond) (2018)

Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes

por Harding, A.-H., Loos, R. J. F., Luan, J., O'Rahilly, S., Wareham, N. J., Barroso, I.
Publicado 2006

Genetic predisposition to obesity leads to increased risk of type 2 diabetes

por Li, S., Zhao, J. H., Luan, J., Langenberg, C., Luben, R. N., Khaw, K. T., Wareham, N. J., Loos, R. J. F.
Publicado 2011

Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response

por Langenberg, C., Pascoe, L., Mari, A., Tura, A., Laakso, M., Frayling, T. M., Barroso, I., Loos, R. J. F., Wareham, N. J., Walker, M.
Publicado 2009

Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: heritabilities

por Souren, N. Y., Paulussen, A. D. C., Loos, R. J. F., Gielen, M., Beunen, G., Fagard, R., Derom, C., Vlietinck, R., Zeegers, M. P.
Publicado 2007

Genetic predisposition influences plasma lipids of participants on habitual diet, but not the response to reductions in dietary intake of saturated fatty acids

por Walker, C.G., Loos, R.J.F., Olson, A.D., Frost, G.S., Griffin, B.A., Lovegrove, J.A., Sanders, T.A.B., Jebb, S.A.
Publicado 2011

Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians

por Li, H., Kilpeläinen, T. O., Liu, C., Zhu, J., Liu, Y., Hu, C., Yang, Z., Zhang, W., Bao, W., Cha, S., Wu, Y., Yang, T., Sekine, A., Choi, B. Y., Yajnik, C. S., Zhou, D., Takeuchi, F., Yamamoto, K., Chan, J. C., Mani, K. R., Been, L. F., Imamura, M., Nakashima, E., Lee, N., Fujisawa, T., Karasawa, S., Wen, W., Joglekar, C. V., Lu, W., Chang, Y., Xiang, Y., Gao, Y., Liu, S., Song, Y., Kwak, S. H., Shin, H. D., Park, K. S., Fall, C. H. D., Kim, J. Y., Sham, P. C., Lam, K. S. L., Zheng, W., Shu, X., Deng, H., Ikegami, H., Krishnaveni, G. V., Sanghera, D. K., Chuang, L., Liu, L., Hu, R., Kim, Y., Daimon, M., Hotta, K., Jia, W., Kooner, J. S., Chambers, J. C., Chandak, G. R., Ma, R. C., Maeda, S., Dorajoo, R., Yokota, M., Takayanagi, R., Kato, N., Lin, X., Loos, R. J. F.
Publicado 2011

Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults

por Zimmermann, E., Ängquist, L. H., Mirza, S. S., Zhao, J. H., Chasman, D. I., Fischer, K., Qi, Q., Smith, A. V., Thinggaard, M., Jarczok, M. N., Nalls, M. A., Trompet, S., Timpson, N. J., Schmidt, B., Jackson, A. U., Lyytikäinen, L. P., Verweij, N., Mueller-Nurasyid, M., Vikström, M., Marques-Vidal, P., Wong, A., Meidtner, K., Middelberg, R. P., Strawbridge, R. J., Christiansen, L., Kyvik, K. O., Hamsten, A., Jääskeläinen, T., Tjønneland, A., Eriksson, J. G., Whitfield, J. B., Boeing, H., Hardy, R., Vollenweider, P., Leander, K., Peters, A., van der Harst, P., Kumari, M., Lehtimäki, T., Meirhaeghe, A., Tuomilehto, J., Jöckel, K.-H., Ben-Shlomo, Y., Sattar, N., Baumeister, S. E., Smith, G. Davey, Casas, J. P., Houston, D. K., März, W., Christensen, K., Gudnason, V., Hu, F. B., Metspalu, A., Ridker, P. M., Wareham, N. J., Loos, R. J. F., Tiemeier, H., Sonestedt, E., Sørensen, T. I. A.
Publicado en Obes Rev (2015)