Sesquiterpene Lactones Isolated from Elephantopus scaber L. Inhibits Human Lymphocyte Proliferation and the Growth of Tumour Cell Lines and Induces Apoptosis In Vitro

por Geetha, B. S., Nair, Mangalam S., Latha, P. G., Remani, P.
Publicado em 2012

Molecular mechanisms of anticancer activity of deoxyelephantopin in cancer cells

por Kabeer, Farha Arakkaveettil, Rajalekshmi, Dhanya Sethumadhavan, Nair, Mangalam Sivasankaran, Prathapan, Remani
Publicado no Integr Med Res (2017)

Corrigendum to “Molecular mechanisms of anticancer activity of Deoxyelephantopin in cancer cells” [Integr Med Res2017, 6, 190–206]

por Kabeer, Farha Arakkaveettil, Rajalekshmi, Dhanya Sethumadhavan, Nair, Mangalam Sivasankaran, Prathapan, Remani
Publicado no Integr Med Res (2019)

Azadirone, a Limonoid Tetranortriterpene, Induces Death Receptors and Sensitizes Human Cancer Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) through a p53...

por Gupta, Subash C., Francis, Sajin K., Nair, Mangalam S., Mo, Yin-Yuan, Aggarwal, Bharat B.
Publicado em 2013

Isodeoxyelephantopin, a Sesquiterpene Lactone Induces ROS Generation, Suppresses NF-κB Activation, Modulates LncRNA Expression and Exhibit Activities Against Breast Cancer

por Verma, Sumit S., Rai, Vipin, Awasthee, Nikee, Dhasmana, Anupam, Rajalaksmi, Dhanya S, Nair, Mangalam S., Gupta, Subash C.
Publicado no Sci Rep (2019)

Nimbolide Sensitizes Human Colon Cancer Cells to TRAIL through Reactive Oxygen Species- and ERK-dependent Up-regulation of Death Receptors, p53, and Bax

por Gupta, Subash C., Reuter, Simone, Phromnoi, Kanokkarn, Park, Byoungduck, Hema, Padmanabhan S., Nair, Mangalam, Aggarwal, Bharat B.
Publicado em 2011

Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment

por Gupta, Subash C., Prasad, Sahdeo, Sethumadhavan, Dhanya R., Nair, Mangalam S., Mo, Yin-Yuan, Aggarwal, Bharat B.
Publicado no Clin Cancer Res (2013)

Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax.

por Gupta, Subash C., Reuter, Simone, Phromnoi, Kanokkarn, Park, Byoungduck, Hema, Padmanabhan S., Nair, Mangalam, Aggarwal, Bharat B.
Publicado no J Biol Chem (2016)

Isodeoxyelephantopin from Elephantopus scaber (Didancao) induces cell cycle arrest and caspase-3-mediated apoptosis in breast carcinoma T47D cells and lung carcinoma A549 cells

por Kabeer, Farha Arakkaveettil, Sreedevi, Geetha Balakrishnan, Nair, Mangalam Sivasankaran, Rajalekshmi, Dhanya Sethumadhavannair, Gopalakrishnan, Latha Panickaparambil, Prathapan, Remani
Publicado em 2014

Crotepoxide Chemosensitizes Tumor Cells through Inhibition of Expression of Proliferation, Invasion, and Angiogenic Proteins Linked to Proinflammatory Pathway

por Prasad, Sahdeo, Yadav, Vivek R., Sundaram, Chitra, Reuter, Simone, Hema, Padmanabhan S., Nair, Mangalam S., Chaturvedi, Madan M., Aggarwal, Bharat B.
Publicado em 2010

Crotepoxide chemosensitizes tumor cells through inhibition of expression of proliferation, invasion, and angiogenic proteins linked to proinflammatory pathway.

por Prasad, Sahdeo, Yadav, Vivek R., Sundaram, Chitra, Reuter, Simone, Hema, Padmanabhan S., Nair, Mangalam S., Chaturvedi, Madan M., Aggarwal, Bharat B.
Publicado no J Biol Chem (2016)

Bharangin, a Diterpenoid Quinonemethide, Abolishes Constitutive and Inducible Nuclear Factor-κB (NF-κB) Activation by Modifying p65 on Cysteine 38 Residue and Reducing Inhibitor of...

por Gupta, Subash C., Kannappan, Ramaswamy, Kim, Jihye, Rahman, Ghazi M., Francis, Sajin K., Raveendran, Reshma, Nair, Mangalam S., Das, Joydip, Aggarwal, Bharat B.
Publicado em 2011

Modification of Cysteine 179 of IκBα Kinase by Nimbolide Leads to Down-regulation of NF-κB-regulated Cell Survival and Proliferative Proteins and Sensitization of Tumor Cells to Ch...

por Gupta, Subash C., Prasad, Sahdeo, Reuter, Simone, Kannappan, Ramaswamy, Yadav, Vivek R., Ravindran, Jayaraj, Hema, Padmanabhan S., Chaturvedi, Madan M., Nair, Mangalam, Aggarwal, Bharat B.
Publicado em 2010

Modification of cysteine 179 of IκBα kinase by nimbolide leads to down-regulation of NF-κB-regulated cell survival and proliferative proteins and sensitization of tumor cells to ch...

por Gupta, Subash C., Prasad, Sahdeo, Reuter, Simone, Kannappan, Ramaswamy, Yadav, Vivek R., Ravindran, Jayaraj, Hema, Padmanabhan S., Chaturvedi, Madan M., Nair, Mangalam, Aggarwal, Bharat B.
Publicado em 2012

Discovery of Natural Product Derived Labdane Appended Triazoles as Potent Pancreatic Lipase Inhibitors

por Jalaja, Renjitha, Leela, Shyni G., Valmiki, Praveen K., Salfeena, Chettiyan Thodi F., Ashitha, Kizhakkan T., Krishna Rao, Venkata Rao D., Nair, Mangalam S., Gopalan, Raghu K., Somappa, Sasidhar B.
Publicado no ACS Med Chem Lett (2018)