Sesquiterpene Lactones Isolated from Elephantopus scaber L. Inhibits Human Lymphocyte Proliferation and the Growth of Tumour Cell Lines and Induces Apoptosis In Vitro

by Geetha, B. S., Nair, Mangalam S., Latha, P. G., Remani, P.
Published 2012

Molecular mechanisms of anticancer activity of deoxyelephantopin in cancer cells

by Kabeer, Farha Arakkaveettil, Rajalekshmi, Dhanya Sethumadhavan, Nair, Mangalam Sivasankaran, Prathapan, Remani
Published in Integr Med Res (2017)

Corrigendum to “Molecular mechanisms of anticancer activity of Deoxyelephantopin in cancer cells” [Integr Med Res2017, 6, 190–206]

by Kabeer, Farha Arakkaveettil, Rajalekshmi, Dhanya Sethumadhavan, Nair, Mangalam Sivasankaran, Prathapan, Remani
Published in Integr Med Res (2019)

Azadirone, a Limonoid Tetranortriterpene, Induces Death Receptors and Sensitizes Human Cancer Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) through a p53...

by Gupta, Subash C., Francis, Sajin K., Nair, Mangalam S., Mo, Yin-Yuan, Aggarwal, Bharat B.
Published 2013

Isodeoxyelephantopin, a Sesquiterpene Lactone Induces ROS Generation, Suppresses NF-κB Activation, Modulates LncRNA Expression and Exhibit Activities Against Breast Cancer

by Verma, Sumit S., Rai, Vipin, Awasthee, Nikee, Dhasmana, Anupam, Rajalaksmi, Dhanya S, Nair, Mangalam S., Gupta, Subash C.
Published in Sci Rep (2019)

Nimbolide Sensitizes Human Colon Cancer Cells to TRAIL through Reactive Oxygen Species- and ERK-dependent Up-regulation of Death Receptors, p53, and Bax

by Gupta, Subash C., Reuter, Simone, Phromnoi, Kanokkarn, Park, Byoungduck, Hema, Padmanabhan S., Nair, Mangalam, Aggarwal, Bharat B.
Published 2011

Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment

by Gupta, Subash C., Prasad, Sahdeo, Sethumadhavan, Dhanya R., Nair, Mangalam S., Mo, Yin-Yuan, Aggarwal, Bharat B.
Published in Clin Cancer Res (2013)

Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax.

by Gupta, Subash C., Reuter, Simone, Phromnoi, Kanokkarn, Park, Byoungduck, Hema, Padmanabhan S., Nair, Mangalam, Aggarwal, Bharat B.
Published in J Biol Chem (2016)

Isodeoxyelephantopin from Elephantopus scaber (Didancao) induces cell cycle arrest and caspase-3-mediated apoptosis in breast carcinoma T47D cells and lung carcinoma A549 cells

by Kabeer, Farha Arakkaveettil, Sreedevi, Geetha Balakrishnan, Nair, Mangalam Sivasankaran, Rajalekshmi, Dhanya Sethumadhavannair, Gopalakrishnan, Latha Panickaparambil, Prathapan, Remani
Published 2014

Crotepoxide Chemosensitizes Tumor Cells through Inhibition of Expression of Proliferation, Invasion, and Angiogenic Proteins Linked to Proinflammatory Pathway

by Prasad, Sahdeo, Yadav, Vivek R., Sundaram, Chitra, Reuter, Simone, Hema, Padmanabhan S., Nair, Mangalam S., Chaturvedi, Madan M., Aggarwal, Bharat B.
Published 2010

Crotepoxide chemosensitizes tumor cells through inhibition of expression of proliferation, invasion, and angiogenic proteins linked to proinflammatory pathway.

by Prasad, Sahdeo, Yadav, Vivek R., Sundaram, Chitra, Reuter, Simone, Hema, Padmanabhan S., Nair, Mangalam S., Chaturvedi, Madan M., Aggarwal, Bharat B.
Published in J Biol Chem (2016)

Bharangin, a Diterpenoid Quinonemethide, Abolishes Constitutive and Inducible Nuclear Factor-κB (NF-κB) Activation by Modifying p65 on Cysteine 38 Residue and Reducing Inhibitor of...

by Gupta, Subash C., Kannappan, Ramaswamy, Kim, Jihye, Rahman, Ghazi M., Francis, Sajin K., Raveendran, Reshma, Nair, Mangalam S., Das, Joydip, Aggarwal, Bharat B.
Published 2011

Modification of Cysteine 179 of IκBα Kinase by Nimbolide Leads to Down-regulation of NF-κB-regulated Cell Survival and Proliferative Proteins and Sensitization of Tumor Cells to Ch...

by Gupta, Subash C., Prasad, Sahdeo, Reuter, Simone, Kannappan, Ramaswamy, Yadav, Vivek R., Ravindran, Jayaraj, Hema, Padmanabhan S., Chaturvedi, Madan M., Nair, Mangalam, Aggarwal, Bharat B.
Published 2010

Modification of cysteine 179 of IκBα kinase by nimbolide leads to down-regulation of NF-κB-regulated cell survival and proliferative proteins and sensitization of tumor cells to ch...

by Gupta, Subash C., Prasad, Sahdeo, Reuter, Simone, Kannappan, Ramaswamy, Yadav, Vivek R., Ravindran, Jayaraj, Hema, Padmanabhan S., Chaturvedi, Madan M., Nair, Mangalam, Aggarwal, Bharat B.
Published 2012

Discovery of Natural Product Derived Labdane Appended Triazoles as Potent Pancreatic Lipase Inhibitors

by Jalaja, Renjitha, Leela, Shyni G., Valmiki, Praveen K., Salfeena, Chettiyan Thodi F., Ashitha, Kizhakkan T., Krishna Rao, Venkata Rao D., Nair, Mangalam S., Gopalan, Raghu K., Somappa, Sasidhar B.
Published in ACS Med Chem Lett (2018)