Limited role of Sirt1 in cancer protection by dietary restriction

Por Herranz, Daniel, Iglesias, Gema, Muñoz-Martín, Maribel, Serrano, Manuel
Publicado em 2011

PI3Kɑ inhibition reduces obesity in mice

Por Lopez-Guadamillas, Elena, Muñoz-Martin, Maribel, Martinez, Sonia, Pastor, Joaquin, Fernandez-Marcos, Pablo J., Serrano, Manuel
Publicado no Aging (Albany NY) (2016)

p21(Cip1) plays a critical role in the physiological adaptation to fasting through activation of PPARα

Por Lopez-Guadamillas, Elena, Fernandez-Marcos, Pablo J., Pantoja, Cristina, Muñoz-Martin, Maribel, Martínez, Dolores, Gómez-López, Gonzalo, Campos-Olivas, Ramón, Valverde, Angela M., Serrano, Manuel
Publicado no Sci Rep (2016)

Therapeutic effect of γ-secretase inhibition in Kras(G12V)-driven non-small cell lung carcinoma through derepression of DUSP1 phosphatase and inhibition of ERK

Por Maraver, Antonio, Fernández-Marcos, Pablo J., Herranz, Daniel, Muñoz-Martin, Maribel, Gomez-Lopez, Gonzalo, Cañamero, Marta, Mulero, Francisca, Megías, Diego, Sanchez-Carbayo, Marta, Shen, Jie, Sanchez-Cespedes, Montserrat, Palomero, Teresa, Ferrando, Adolfo, Serrano, Manuel
Publicado em 2012

Pharmacological Inhibition of PI3K Reduces Adiposity and Metabolic Syndrome in Obese Mice and Rhesus Monkeys

Por Ortega-Molina, Ana, Lopez-Guadamillas, Elena, Mattison, Julie A., Mitchell, Sarah J., Muñoz-Martin, Maribel, Iglesias, Gema, Gutierrez, Vincent M., Vaughan, Kelli L., Szarowicz, Mark D., González-García, Ismael, López, Miguel, Cebrián, David, Martinez, Sonia, Pastor, Joaquin, de Cabo, Rafael, Serrano, Manuel
Publicado no Cell Metab (2015)

NOTCH pathway inactivation promotes bladder cancer progression

Por Maraver, Antonio, Fernandez-Marcos, Pablo J., Cash, Timothy P., Mendez-Pertuz, Marinela, Dueñas, Marta, Maietta, Paolo, Martinelli, Paola, Muñoz-Martin, Maribel, Martínez-Fernández, Mónica, Cañamero, Marta, Roncador, Giovanna, Martinez-Torrecuadrada, Jorge L., Grivas, Dimitrios, de la Pompa, Jose Luis, Valencia, Alfonso, Paramio, Jesús M., Real, Francisco X., Serrano, Manuel
Publicado no J Clin Invest (2015)

A versatile drug delivery system targeting senescent cells

Por Muñoz‐Espín, Daniel, Rovira, Miguel, Galiana, Irene, Giménez, Cristina, Lozano‐Torres, Beatriz, Paez‐Ribes, Marta, Llanos, Susana, Chaib, Selim, Muñoz‐Martín, Maribel, Ucero, Alvaro C, Garaulet, Guillermo, Mulero, Francisca, Dann, Stephen G, VanArsdale, Todd, Shields, David J, Bernardos, Andrea, Murguía, José Ramón, Martínez‐Máñez, Ramón, Serrano, Manuel
Publicado no EMBO Mol Med (2018)