A versatile drug delivery system targeting senescent cells

Senescent cells accumulate in multiple aging‐associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal β‐galactosidase activity of senescent cells to design a drug delivery system based on the encapsulatio...

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Udgivet i:EMBO Mol Med
Main Authors: Muñoz‐Espín, Daniel, Rovira, Miguel, Galiana, Irene, Giménez, Cristina, Lozano‐Torres, Beatriz, Paez‐Ribes, Marta, Llanos, Susana, Chaib, Selim, Muñoz‐Martín, Maribel, Ucero, Alvaro C, Garaulet, Guillermo, Mulero, Francisca, Dann, Stephen G, VanArsdale, Todd, Shields, David J, Bernardos, Andrea, Murguía, José Ramón, Martínez‐Máñez, Ramón, Serrano, Manuel
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127887/
https://ncbi.nlm.nih.gov/pubmed/30012580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809355
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