Metalloproteinase and inhibitor expression profiling of resorbing cartilage reveals pro-collagenase activation as a critical step for collagenolysis

Por Milner, Jennifer M, Rowan, Andrew D, Cawston, Tim E, Young, David A
Publicado em 2006

Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis

Por Milner, Jennifer M, Kevorkian, Lara, Young, David A, Jones, Debra, Wait, Robin, Donell, Simon T, Barksby, Emma, Patterson, Angela M, Middleton, Jim, Cravatt, Benjamin F, Clark, Ian M, Rowan, Andrew D, Cawston, Timothy E
Publicado em 2006

Matriptase Induction of Metalloproteinase‐Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms

Por Wilkinson, David J., Habgood, Angela, Lamb, Heather K., Thompson, Paul, Hawkins, Alastair R., Désilets, Antoine, Leduc, Richard, Steinmetzer, Torsten, Hammami, Maya, Lee, Melody S., Craik, Charles S., Watson, Sharon, Lin, Hua, Milner, Jennifer M., Rowan, Andrew D.
Publicado no Arthritis Rheumatol (2017)

The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover

Por Wilkinson, David J., Desilets, Antoine, Lin, Hua, Charlton, Sarah, del Carmen Arques, Maria, Falconer, Adrian, Bullock, Craig, Hsu, Yu-Chen, Birchall, Kristian, Hawkins, Alastair, Thompson, Paul, Ferrell, William R., Lockhart, John, Plevin, Robin, Zhang, Yadan, Blain, Emma, Lin, Shu-Wha, Leduc, Richard, Milner, Jennifer M., Rowan, Andrew D.
Publicado no Sci Rep (2017)