Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway

Por Vermijlen, David, Luo, Dianzhong, Froelich, Christopher J, Medema, Jan P, Kummer, Jean A, Willems, Erik, Braet, Filip, Wisse, Eddie
Publicado em 2004

Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids

Por Fiore, Donatella, Ramesh, Prashanthi, Proto, Maria C., Piscopo, Chiara, Franceschelli, Silvia, Anzelmo, Serena, Medema, Jan P., Bifulco, Maurizio, Gazzerro, Patrizia
Publicado no Front Pharmacol (2018)

Stromal SPOCK1 supports invasive pancreatic cancer growth

Por Veenstra, Veronique L., Damhofer, Helene, Waasdorp, Cynthia, Steins, Anne, Kocher, Hemant M., Medema, Jan P., van Laarhoven, Hanneke W., Bijlsma, Maarten F
Publicado no Mol Oncol (2017)

Granzyme B-dependent proteolysis acts as a switch to enhance the pro-inflammatory activity of IL-1α

Por Afonina, Inna S., Tynan, Graham A., Logue, Susan E., Cullen, Sean P., Bots, Michael, Lüthi, Alexander U., Reeves, Emer P., McElvaney, Noel G., Medema, Jan P., Lavelle, Ed C., Martin, Seamus J.
Publicado em 2011