Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids

Colorectal cancer (CRC), like other tumor types, is a highly heterogeneous disease. Within the tumor bulk, intra-tumoral heterogeneity is also ascribable to Cancer Stem Cells (CSCs) subpopulation, characterized by high chemoresistance and the unique ability to retain tumorigenic potential, thus asso...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Fiore, Donatella, Ramesh, Prashanthi, Proto, Maria C., Piscopo, Chiara, Franceschelli, Silvia, Anzelmo, Serena, Medema, Jan P., Bifulco, Maurizio, Gazzerro, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758598/
https://ncbi.nlm.nih.gov/pubmed/29354056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00949
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