Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer

In a high percentage (≥85%) of both sporadic and familial adenomatous polyposis forms of colorectal cancer (CRC), the inactivation of the APC tumor suppressor gene initiates tumor formation and modulates the Wnt/β-Catenin transduction pathways involved in the control of cell proliferation, adhesion...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Proto, Maria Chiara, Fiore, Donatella, Piscopo, Chiara, Franceschelli, Silvia, Bizzarro, Valentina, Laezza, Chiara, Lauro, Gianluigi, Feoli, Alessandra, Tosco, Alessandra, Bifulco, Giuseppe, Sbardella, Gianluca, Bifulco, Maurizio, Gazzerro, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601949/
https://ncbi.nlm.nih.gov/pubmed/28916833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11688-x
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