NIH TRND Program: Successes in Preclinical Therapeutic Development

Por McKew, John C., Pilon, Andre M.
Publicado em 2012

Playing Well with Others! Initiating and sustaining successful collaborations between Industry, Academia and Government

Por Thomas, Craig J., McKew, John C.
Publicado no Curr Top Med Chem (2014)

Phenotypic screens as a renewed approach for drug discovery

Por Zheng, Wei, Thorne, Natasha, McKew, John C.
Publicado no Drug Discov Today (2013)

An Alternative Direct Compound Dispensing Method Using the HP D300 Digital Dispenser

Por Jones, Raisa, Zheng, Wei, McKew, John C., Chen, Catherine Z.
Publicado em 2013

New Financial and Research Models for Pediatric Orphan Drug Development - Focus on the NCATS TRND Program

Por Shen, John, Grewal, Gurmit, Pilon, Andre M., McKew, John C.
Publicado em 2014

Evaluation of Cholesterol Reduction Activity of Methyl-β-cyclodextrin Using Differentiated Human Neurons and Astrocytes

Por Swaroop, Manju, Thorne, Natasha, Rao, Mahendra S., Austin, Christopher P., McKew, John C., Zheng, Wei
Publicado em 2012

A High Throughput Screening Assay for Assessing Viability of Cryptococcus neoformans under Nutrient Starvation Condition

Por Dehdashti, Seameen J., Abbott, Jennifer, Nguyen, Dac-Trung, McKew, John C., Williamson, Peter R., Zheng, Wei
Publicado no Anal Bioanal Chem (2013)

A Phenotypic Compound Screening Assay for Lysosomal Storage Diseases

Por Xu, Miao, Liu, Ke, Swaroop, Manju, Sun, Wei, Dehdashti, Seameen J., McKew, John C., Zheng, Wei
Publicado no J Biomol Screen (2013)

A Quantitative High Throughput Assay for Identifying Gametocytocidal Compounds

Por Tanaka, Takeshi Q., Dehdashti, Seameen J., Nguyen, Dac-Trung, McKew, John C., Zheng, Wei, Williamson, Kim C.
Publicado em 2013

ERK and β-arrestin interaction: a converging-point of signaling pathways for multiple types of cell-surface receptors

Por Eishingdrelo, Haifeng, Sun, Wei, Li, Hua, Wang, Li, Eishingdrelo, Alex, Dai, Sheng, McKew, John C., Zheng, Wei
Publicado no J Biomol Screen (2014)

Plasma and Tissue Concentrations of α-Tocopherol and δ-Tocopherol Following High Dose Dietary Supplementation in Mice

Por Baxter, Laura L., Marugan, Juan J., Xiao, Jingbo, Incao, Art, McKew, John C., Zheng, Wei, Pavan, William J.
Publicado em 2012

High throughput cell-based assay for identification of glycolate oxidase inhibitors as a potential treatment for Primary Hyperoxaluria Type 1

Por Wang, Mengqiao, Xu, Miao, Long, Yan, Fargue, Sonia, Southall, Noel, Hu, Xin, McKew, John C., Danpure, Christopher J., Zheng, Wei
Publicado no Sci Rep (2016)

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress

Por Thorne, Natasha, Malik, Nasir, Shah, Sonia, Zhao, Jean, Class, Bradley, Aguisanda, Francis, Southall, Noel, Xia, Menghang, McKew, John C., Rao, Mahendra, Zheng, Wei
Publicado no Stem Cells Transl Med (2016)

Chemical signatures and new drug targets for gametocytocidal drug development

Por Sun, Wei, Tanaka, Takeshi Q., Magle, Crystal T., Huang, Wenwei, Southall, Noel, Huang, Ruili, Dehdashti, Seameen J., McKew, John C., Williamson, Kim C., Zheng, Wei
Publicado em 2014

A High-throughput Screening Assay for Determining Cellular Levels of Total Tau Protein

Por Dehdashti, Seameen J., Zheng, Wei, Gever, Joel R., Wilhelm, Robert, Nguyen, Dac-Trung, Sittampalam, Gurusingham, McKew, John C., Austin, Christopher P., Prusiner, Stanley B.
Publicado em 2013

Rapid Identification of Antifungal Compounds against Exserohilum rostratum Using High Throughput Drug Repurposing Screens

Por Sun, Wei, Park, Yoon-Dong, Sugui, Janyce A., Fothergill, Annette, Southall, Noel, Shinn, Paul, McKew, John C., Kwon-Chung, Kyung J., Zheng, Wei, Williamson, Peter R.
Publicado em 2013

Correction: Rapid Identification of Antifungal Compounds against Exserohilum rostratum Using High Throughput Drug Repurposing Screens

Por Sun, Wei, Park, Yoon-Dong, Sugui, Janyce A., Fothergill, Annette, Southall, Noel, Shinn, Paul, McKew, John C., Kwon-Chung, Kyung J., Zheng, Wei, Williamson, Peter R.
Publicado em 2013

Correction: Rapid Identification of Antifungal Compounds against Exserohilum rostratum Using High Throughput Drug Repurposing Screens

Por Sun, Wei, Park, Yoon-Dong, Sugui, Janyce A., Fothergill, Annette, Southall, Noel, Shinn, Paul, McKew, John C., Kwon-Chung, Kyung J., Zheng, Wei, Williamson, Peter R.
Publicado em 2013

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

Por Kouznetsova, Jennifer, Sun, Wei, Martínez-Romero, Carles, Tawa, Gregory, Shinn, Paul, Chen, Catherine Z, Schimmer, Aaron, Sanderson, Philip, McKew, John C, Zheng, Wei, García-Sastre, Adolfo
Publicado no Emerg Microbes Infect (2014)

In vitro evaluation of imidazo[4,5-c]quinolin-2-ones as gametocytocidal antimalarial agents

Por Patel, Paresma R., Sun, Wei, Kim, Myunghoon, Huang, Xiuli, Sanderson, Philip E., Tanaka, Takeshi Q., McKew, John C., Simeonov, Anton, Williamson, Kim C., Zheng, Wei, Huang, Wenwei
Publicado no Bioorg Med Chem Lett (2016)