Specialized interfaces of Smc5/6 control hinge stability and DNA association

מאת Alt, Aaron, Dang, Hung Q., Wells, Owen S., Polo, Luis M., Smith, Matt A., McGregor, Grant A., Welte, Thomas, Lehmann, Alan R., Pearl, Laurence H., Murray, Johanne M., Oliver, Antony W.
הוצא לאור ב Nat Commun (2017)

Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease

מאת van der Crabben, Saskia N., Hennus, Marije P., McGregor, Grant A., Ritter, Deborah I., Nagamani, Sandesh C.S., Wells, Owen S., Harakalova, Magdalena, Chinn, Ivan K., Alt, Aaron, Vondrova, Lucie, Hochstenbach, Ron, van Montfrans, Joris M., Terheggen-Lagro, Suzanne W., van Lieshout, Stef, van Roosmalen, Markus J., Renkens, Ivo, Duran, Karen, Nijman, Isaac J., Kloosterman, Wigard P., Hennekam, Eric, Orange, Jordan S., van Hasselt, Peter M., Wheeler, David A., Palecek, Jan J., Lehmann, Alan R., Oliver, Antony W., Pearl, Laurence H., Plon, Sharon E., Murray, Johanne M., van Haaften, Gijs
הוצא לאור ב J Clin Invest (2016)

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer

מאת Dreyer, Stephan B., Upstill-Goddard, Rosie, Paulus-Hock, Viola, Paris, Clara, Lampraki, Eirini-Maria, Dray, Eloise, Serrels, Bryan, Caligiuri, Giuseppina, Rebus, Selma, Plenker, Dennis, Galluzzo, Zachary, Brunton, Holly, Cunningham, Richard, Tesson, Mathias, Nourse, Craig, Bailey, Ulla-Maja, Jones, Marc, Moran-Jones, Kim, Wright, Derek W., Duthie, Fraser, Oien, Karin, Evers, Lisa, McKay, Colin J., McGregor, Grant A., Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephan, Dziubinski, Michele L., Candido, Juliana, Balkwill, Frances, Barry, Simon T., Grützmann, Robert, Rahib, Lola, Johns, Amber, Pajic, Marina, Froeling, Fieke E.M., Beer, Phillip, Musgrove, Elizabeth A., Petersen, Gloria M., Ashworth, Alan, Frame, Margaret C., Crawford, Howard C., Simeone, Diane M., Lord, Chris, Mukhopadhyay, Debabrata, Pilarsky, Christian, Tuveson, David A., Cooke, Susanna L., Jamieson, Nigel B., Morton, Jennifer P., Sansom, Owen J., Bailey, Peter J., Biankin, Andrew V., Chang, David K.
הוצא לאור ב Gastroenterology (2021)