Low rate of TP53 germline mutations in breast cancer/sarcoma families not fulfilling classical criteria for Li-Fraumeni syndrome

Por Evans, D, Birch, J, Thorneycroft, M, McGown, G, Lalloo, F, Varley, J
Publicado em 2002

Proximal 6q, a region showing allele loss in primary breast cancer.

Por Orphanos, V., McGown, G., Hey, Y., Boyle, J. M., Santibanez-Koref, M.
Publicado em 1995

Exclusion of the genes CDKN2 and PTEN as causative gene defects in Li–Fraumeni syndrome

Por Burt, E C, McGown, G, Thorncroft, M, James, L A, Birch, J M, Varley, J M
Publicado em 1999

Allelic imbalance of chromosome 6q in ovarian tumours.

Por Orphanos, V., McGown, G., Hey, Y., Thorncroft, M., Santibanez-Koref, M., Russell, S. E., Hickey, I., Atkinson, R. J., Boyle, J. M.
Publicado em 1995

A novel TP53 splicing mutation in a Li-Fraumeni syndrome family: a patient with Wilms' tumour is not a mutation carrier.

Por Varley, J. M., McGown, G., Thorncroft, M., White, G. R., Tricker, K. J., Kelsey, A. M., Birch, J. M., Evans, D. G.
Publicado em 1998

An extended Li-Fraumeni kindred with gastric carcinoma and a codon 175 mutation in TP53.

Por Varley, J M, McGown, G, Thorncroft, M, Tricker, K J, Teare, M D, Santibanez-Koref, M F, Martin, J, Birch, J M, Evans, D G
Publicado em 1995

A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours

Por Khan, O A, Gore, M, Lorigan, P, Stone, J, Greystoke, A, Burke, W, Carmichael, J, Watson, A J, McGown, G, Thorncroft, M, Margison, G P, Califano, R, Larkin, J, Wellman, S, Middleton, M R
Publicado em 2011

O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib

Por Watson, A J, Middleton, M R, McGown, G, Thorncroft, M, Ranson, M, Hersey, P, McArthur, G, Davis, I D, Thomson, D, Beith, J, Haydon, A, Kefford, R, Lorigan, P, Mortimer, P, Sabharwal, A, Hayward, O, Margison, G P
Publicado em 2009