α-Synuclein: A therapeutic target for Parkinson’s disease?

Por Maguire-Zeiss, Kathleen A.
Publicado em 2008

Misfolded α-synuclein and toll-like receptors: therapeutic targets for Parkinson’s disease

Por Béraud, Dawn, Maguire-Zeiss, Kathleen A.
Publicado em 2012

Gene Therapy in Parkinson’s Disease: Rationale and Current Status

Por Feng, Li Rebekah, Maguire-Zeiss, Kathleen A.
Publicado em 2010

Immune-Directed Gene Therapeutic Development for Alzheimer's, Prion, and Parkinson's Diseases

Por Maguire-Zeiss, Kathleen A., Federoff, Howard J.
Publicado em 2008

Dopamine and paraquat enhance α-synuclein-induced alterations in membrane conductance

Por Feng, Li Rebekah, Maguire-Zeiss, Kathleen A.
Publicado em 2011

Mutant α-Synuclein Overexpression Mediates Early Proinflammatory Activity

Por Su, Xiaomin, Federoff, Howard J., Maguire-Zeiss, Kathleen A.
Publicado em 2009

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates

Por Daniele, Stefano G., Edwards, Amanda A., Maguire-Zeiss, Kathleen A.
Publicado em 2014

α-Synuclein mediates alterations in membrane conductance: a potential role for α-synuclein oligomers in cell vulnerability

Por Feng, Li Rebekah, Federoff, Howard J., Vicini, Stefano, Maguire-Zeiss, Kathleen A.
Publicado em 2010

Parkinson’s Disease

Por Mhyre, Timothy R., Boyd, James T., Hamill, Robert W., Maguire-Zeiss, Kathleen A.
Publicado no Subcell Biochem (2012)

Inflammation alters AMPA-stimulated calcium responses in dorsal striatal D2 but not D1 spiny projection neurons

Por Winland, Carissa D., Welsh, Nora, Sepulveda-Rodriguez, Alberto, Vicini, Stefano, Maguire-Zeiss, Kathleen A.
Publicado no Eur J Neurosci (2017)

Synuclein activates microglia in a model of Parkinson’s Disease

Por Su, Xiaomin, Maguire-Zeiss, Kathleen A., Giuliano, Rita, Prifti, Landa, Venkatesh, Karthik, Federoff, Howard J.
Publicado em 2007

Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders

Por Daniele, Stefano G., Béraud, Dawn, Davenport, Connor, Cheng, Kui, Yin, Hang, Maguire-Zeiss, Kathleen A.
Publicado no Sci Signal (2015)

Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1

Por Allen, Megan, Ghosh, Suhasini, Ahern, Gerard P., Villapol, Sonia, Maguire-Zeiss, Kathleen A., Conant, Katherine
Publicado no Sci Rep (2016)

Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model

Por Rebeck GW, Lashuel Hilal A, Maguire-Zeiss Kathleen, Feng Li, Dumanis Sonya B, Khandelwal Preeti J, Moussa Charbel EH
Publicado em 2010-11-01

Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model

Por Khandelwal, Preeti J, Dumanis, Sonya B, Feng, Li Rebekah, Maguire-Zeiss, Kathleen, Rebeck, GW, Lashuel, Hilal A, Moussa, Charbel EH
Publicado em 2010

Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation

Por Conant, Katherine, Daniele, Stefano, Bozzelli, P. Lorenzo, Abdi, Tsion, Edwards, Amanda, Szklarczyk, Arek, Olchefske, India, Ottenheimer, David, Maguire-Zeiss, Kathleen
Publicado no J Neuroinflammation (2017)

α-Synuclein Alters Toll-Like Receptor Expression

Por Béraud, Dawn, Twomey, Margaret, Bloom, Benjamin, Mittereder, Andrew, Ton, Vy, Neitzke, Katherine, Chasovskikh, Sergey, Mhyre, Timothy R., Maguire-Zeiss, Kathleen A.
Publicado em 2011

Proteomic analysis of peripheral leukocytes in Alzheimer’s disease patients treated with divalproex sodium

Por Mhyre, Timothy R., Loy, Rebekah, Tariot, Pierre N., Profenno, Louis A., Maguire-Zeiss, Kathleen A., Zhang, Dabao, Coleman, Paul D., Federoff, Howard J.
Publicado em 2007

Human Interleukin-10 Gene Transfer Is Protective in a Rat Model of Parkinson’s Disease

Por Johnston, Louisa C, Su, Xiaomin, Maguire-Zeiss, Kathleen, Horovitz, Karen, Ankoudinova, Irina, Guschin, Dmitry, Hadaczek, Piotr, Federoff, Howard J, Bankiewicz, Krystof, Forsayeth, John
Publicado em 2008

Development of Inducible Leucine-rich Repeat Kinase 2 (LRRK2) Cell Lines for Therapeutics Development in Parkinson’s Disease

Por Huang, Liang, Shimoji, Mika, Wang, Juan, Shah, Salim, Kamila, Sukanta, Biehl, Edward R., Lim, Seung, Chang, Allison, Maguire-Zeiss, Kathleen A., Su, Xiaomin, Federoff, Howard J.
Publicado em 2013