Aurora B Interacts with NIR-p53, Leading to p53 Phosphorylation in Its DNA-binding Domain and Subsequent Functional Suppression

Por Wu, Liming, Ma, Chi A., Zhao, Yongge, Jain, Ashish
Publicado em 2011

Impaired dendritic-cell function in ectodermal dysplasia with immune deficiency is linked to defective NEMO ubiquitination

Por Temmerman, Stephane T., Ma, Chi A., Borges, Louis, Kubin, Marek, Liu, Shuying, Derry, Jonathan M. J., Jain, Ashish
Publicado em 2006

Impaired regulation of NF-κB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice

Por Zhang, Jun, Stirling, Brigid, Temmerman, Stephane T., Ma, Chi A., Fuss, Ivan J., Derry, Jonathan M.J., Jain, Ashish
Publicado em 2006

Dendritic cells from humans with hypomorphic mutations in NEMO have impaired mitogen-activated protein kinase activity

Por Ma, Chi A., Wang, Hong-Ying, Temmerman, Stephane, Zhao, Yongge, Wu, Liming, Hornung, Ronald L., Wara, Diane, Jain, Ashish
Publicado em 2011

Novel INHAT Repressor (NIR) is required for early lymphocyte development

Por Ma, Chi A., Pusso, Antonia, Wu, Liming, Zhao, Yongge, Hoffmann, Victoria, Notarangelo, Luigi D., Fowlkes, B. J., Jain, Ashish
Publicado em 2014

CYLD and the NEMO Zinc Finger Regulate Tumor Necrosis Factor Signaling and Early Embryogenesis

Por Zhao, Yongge, Ma, Chi A., Wu, Liming, Iwai, Kazuhiro, Ashwell, Jonathan D., Oltz, Eugene M., Ballard, Dean W., Jain, Ashish
Publicado no J Biol Chem (2015)

Specific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation

Por Jain, Ashish, Ma, Chi A., Lopez-Granados, Eduardo, Means, Gary, Brady, William, Orange, Jordan S., Liu, Shuying, Holland, Steven, Derry, Jonathan M.J.
Publicado em 2004

The Deubiquitinase CYLD Targets Smad7 Protein to Regulate Transforming Growth Factor β (TGF-β) Signaling and the Development of Regulatory T Cells

Por Zhao, Yongge, Thornton, Angela M., Kinney, Matthew C., Ma, Chi A., Spinner, Jacob J., Fuss, Ivan J., Shevach, Ethan M., Jain, Ashish
Publicado em 2011

Defective nuclear IKKα function in patients with ectodermal dysplasia with immune deficiency

Por Temmerman, Stephane T., Ma, Chi A., Zhao, Yongge, Keenan, Jeffrey, Aksentijevich, Ivona, Fessler, Margaret, Brown, Margaret R., Knutsen, Alan, Shapiro, Ralph, Jain, Ashish
Publicado em 2011

A Novel Mutation in NFKBIA/IKBA Results in a Degradation-Resistant N-Truncated Protein and Is Associated With Ectodermal Dysplasia With Immunodeficiency

Por Lopez-Granados, Eduardo, Keenan, Jeffrey E., Kinney, Matthew C., Leo, Harvey, Jain, Neal, Ma, Chi A., Quinones, Ralph, Gelfand, Erwin W., Jain, Ashish
Publicado em 2008

Antibody deficiency associated with an inherited autosomal dominant mutation in TWEAK

Por Wang, Hong-Ying, Ma, Chi A., Zhao, Yongge, Fan, Xiying, Zhou, Qing, Edmonds, Pamela, Uzel, Gulbu, Oliveira, Joao Bosco, Orange, Jordan, Jain, Ashish
Publicado em 2013

PD-L1 up-regulation restrains Th17 cell differentiation in STAT3 loss- and STAT1 gain-of-function patients

Por Zhang, Yuan, Ma, Chi A., Lawrence, Monica G., Break, Timothy J., O’Connell, Michael P., Lyons, Jonathan J., López, Diego B., Barber, John S., Zhao, Yongge, Barber, Daniel L., Freeman, Alexandra F., Holland, Steven M., Lionakis, Michail S., Milner, Joshua D.
Publicado no J Exp Med (2017)

CD40 agonist antibody mediated improvement of chronic Cryptosporidium infection in patients with X- linked hyper IgM syndrome

Por Fan, Xiying, Upadhyaya, Bhaskar, Wu, Liming, Koh, Christopher, Santín-Durán, Mónica, Pittaluga, Stefania, Uzel, Gulbu, Kleiner, David, Williams, Ester, Ma, Chi A., Bodansky, Aaron, Oliveira, Joao B., Edmonds, Pamela, Hornung, Ronald, Wong, Duane W., Fayer, Ronald, Fleisher, Tom, Heller, Theo, Prussin, Calman, Jain, Ashish
Publicado em 2012

Somatic STAT5b gain-of-function mutations in early onset nonclonal eosinophilia, urticaria, dermatitis, and diarrhea

Por Ma, Chi A., Xi, Liqiang, Cauff, Brian, DeZure, Adam, Freeman, Alexandra F., Hambleton, Sophie, Kleiner, Gary, Leahy, T. Ronan, O’Sullivan, Maureen, Makiya, Michelle, O’Regan, Grainne, Pittaluga, Stefania, Niemela, Julie, Stoddard, Jennifer, Rosenzweig, Sergio D., Raffeld, Mark, Klion, Amy D., Milner, Joshua D.
Publicado no Blood (2017)

Inherited SLP76 deficiency in humans causes severe combined immunodeficiency, neutrophil and platelet defects

Por Lev, Atar, Lee, Yu Nee, Sun, Guangping, Hallumi, Enas, Simon, Amos J., Zrihen, Keren S., Levy, Shiran, Beit Halevi, Tal, Papazian, Maria, Shwartz, Neta, Somekh, Ido, Levy-Mendelovich, Sarina, Wolach, Baruch, Gavrieli, Ronit, Vernitsky, Helly, Barel, Ortal, Javasky, Elisheva, Stauber, Tali, Ma, Chi A., Zhang, Yuan, Amariglio, Ninette, Rechavi, Gideon, Hendel, Ayal, Yablonski, Deborah, Milner, Joshua D., Somech, Raz
Publicado no J Exp Med (2020)

Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses

Por Spencer, Sarah, Köstel Bal, Sevgi, Egner, William, Lango Allen, Hana, Raza, Syed I., Ma, Chi A., Gürel, Meltem, Zhang, Yuan, Sun, Guangping, Sabroe, Ruth A., Greene, Daniel, Rae, William, Shahin, Tala, Kania, Katarzyna, Ardy, Rico Chandra, Thian, Marini, Staples, Emily, Pecchia-Bekkum, Annika, Worrall, William P.M., Stephens, Jonathan, Brown, Matthew, Tuna, Salih, York, Melanie, Shackley, Fiona, Kerrin, Diarmuid, Sargur, Ravishankar, Condliffe, Alison, Tipu, Hamid Nawaz, Kuehn, Hye Sun, Rosenzweig, Sergio D., Turro, Ernest, Tavaré, Simon, Thrasher, Adrian J., Jodrell, Duncan Ian, Smith, Kenneth G.C., Boztug, Kaan, Milner, Joshua D., Thaventhiran, James E.D.
Publicado no J Exp Med (2019)

Germline hypomorphic CARD11 mutations in severe atopic disease

Por Ma, Chi A, Stinson, Jeffrey R, Zhang, Yuan, Abbott, Jordan K, Weinreich, Michael A, Hauk, Pia J, Reynolds, Paul R, Lyons, Jonathan J, Nelson, Celeste G, Ruffo, Elisa, Dorjbal, Batsukh, Glauzy, Salomé, Yamakawa, Natsuko, Arjunaraja, Swadhinya, Voss, Kelsey, Stoddard, Jennifer, Niemela, Julie, Zhang, Yu, Rosenzweig, Sergio D, McElwee, Joshua J, DiMaggio, Thomas, Matthews, Helen F, Jones, Nina, Stone, Kelly D, Palma, Alejandro, Oleastro, Matías, Prieto, Emma, Bernasconi, Andrea R, Dubra, Geronimo, Danielian, Silvia, Zaiat, Jonathan, Marti, Marcelo A, Kim, Brian, Cooper, Megan A, Romberg, Neil D, Meffre, Eric, Gelfand, Erwin W, Snow, Andrew L, Milner, Joshua D
Publicado no Nat Genet (2017)

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

Por Milner, Joshua D., Vogel, Tiphanie P., Forbes, Lisa, Ma, Chi A., Stray-Pedersen, Asbjørg, Niemela, Julie E., Lyons, Jonathan J., Engelhardt, Karin R., Zhang, Yu, Topcagic, Nermina, Roberson, Elisha D. O., Matthews, Helen, Verbsky, James W., Dasu, Trivikram, Vargas-Hernandez, Alexander, Varghese, Nidhy, McClain, Kenneth L., Karam, Lina B., Nahmod, Karen, Makedonas, George, Mace, Emily M., Sorte, Hanne S., Perminow, Gøri, Rao, V. Koneti, O’Connell, Michael P., Price, Susan, Su, Helen C., Butrick, Morgan, McElwee, Joshua, Hughes, Jason D., Willet, Joseph, Swan, David, Xu, Yaobo, Santibanez-Koref, Mauro, Slowik, Voytek, Dinwiddie, Darrell L., Ciaccio, Christina E., Saunders, Carol J., Septer, Seth, Kingsmore, Stephen F., White, Andrew J., Cant, Andrew J., Hambleton, Sophie, Cooper, Megan A.
Publicado no Blood (2015)

Hypomorphic CARD11 mutations associated with diverse immunologic phenotypes with or without atopic disease.

Por Dorjbal, Batsukh, Stinson, Jeffrey R., Ma, Chi A., Weinreich, Michael A., Miraghazadeh, Bahar, Hartberger, Julia M., Frey-Jakobs, Stefanie, Weidinger, Stephan, Moebus, Lena, Franke, Andre, Schäffer, Alejandro A., Bulashevska, Alla, Fuchs, Sebastian, Ehl, Stephan, Limaye, Sandhya, Arkwright, Peter D., Briggs, Tracy A., Langley, Claire, Bethune, Claire, Whyte, Andrew F., Alachkar, Hana, Nejentsev, Sergey, DiMaggio, Thomas, Nelson, Celeste G., Stone, Kelly D., Nason, Martha, Brittain, Erica H., Oler, Andrew J., Veltri, Daniel P., Leahy, T. Ronan, Conlon, Niall, Poli, Maria C., Borzutzky, Arturo, Cohen, Jeffrey I., Davis, Joie, Lambert, Michele P., Romberg, Neil, Sullivan, Kathleen E., Paris, Kenneth, Freeman, Alexandra F., Lucas, Laura, Chandrakasan, Shanmuganathan, Savic, Sinisa, Hambleton, Sophie, Patel, Smita Y, Jordan, Michael B., Theos, Amy, Lebensburger, Jeffrey, Atkinson, T. Prescott, Torgerson, Troy R., Chinn, Ivan K., Milner, Joshua D., Grimbacher, Bodo, Cook, Matthew C., Snow, Andrew L.
Publicado no J Allergy Clin Immunol (2018)