Evidence for different mechanisms of ‘unhooking’ for melphalan and cisplatin-induced DNA interstrand cross-links <it>in vitro</it> and in clinical acquired resistant tumour samples...

by Spanswick Victoria J, Lowe Helen L, Newton Claire, Bingham John P, Bagnobianchi Alessia, Kiakos Konstantinos, Craddock Charles, Ledermann Jonathan A, Hochhauser Daniel, Hartley John A
Published 2012-09-01

Evidence for different mechanisms of ‘unhooking’ for melphalan and cisplatin-induced DNA interstrand cross-links in vitro and in clinical acquired resistant tumour samples

by Spanswick, Victoria J, Lowe, Helen L, Newton, Claire, Bingham, John P, Bagnobianchi, Alessia, Kiakos, Konstantinos, Craddock, Charles, Ledermann, Jonathan A, Hochhauser, Daniel, Hartley, John A
Published 2012

A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer

by Ohnmacht, Stephan A, Marchetti, Chiara, Gunaratnam, Mekala, Besser, Rachael J, Haider, Shozeb M, Di Vita, Gloria, Lowe, Helen L, Mellinas-Gomez, Maria, Diocou, Seckou, Robson, Mathew, Šponer, Jiri, Islam, Barira, Barbara Pedley, R, Hartley, John A, Neidle, Stephen
Published in Sci Rep (2015)

VEROnA Protocol: A Pilot, Open-Label, Single-Arm, Phase 0, Window-of-Opportunity Study of Vandetanib-Eluting Radiopaque Embolic Beads (BTG-002814) in Patients With Resectable Liver...

by Beaton, Laura, Tregidgo, Henry F J, Znati, Sami A, Forsyth, Sharon, Clarkson, Matthew J, Bandula, Steven, Chouhan, Manil, Lowe, Helen L, Zaw Thin, May, Hague, Julian, Sharma, Dinesh, Pollok, Joerg-Matthias, Davidson, Brian R, Raja, Jowad, Munneke, Graham, Stuckey, Daniel J, Bascal, Zainab A, Wilde, Paul E, Cooper, Sarah, Ryan, Samantha, Czuczman, Peter, Boucher, Eveline, Hartley, John A, Lewis, Andrew L, Jansen, Marnix, Meyer, Tim, Sharma, Ricky A
Published in JMIR Res Protoc (2019)

Phylogenetic ctDNA analysis depicts early stage lung cancer evolution

by Abbosh, Christopher, Birkbak, Nicolai J., Wilson, Gareth A., Jamal-Hanjani, Mariam, Constantin, Tudor, Salari, Raheleh, Le Quesne, John, Moore, David A, Veeriah, Selvaraju, Rosenthal, Rachel, Marafioti, Teresa, Kirkizlar, Eser, Watkins, Thomas B K, McGranahan, Nicholas, Ward, Sophia, Martinson, Luke, Riley, Joan, Fraioli, Francesco, Al Bakir, Maise, Grönroos, Eva, Zambrana, Francisco, Endozo, Raymondo, Bi, Wenya Linda, Fennessy, Fiona M., Sponer, Nicole, Johnson, Diana, Laycock, Joanne, Shafi, Seema, Czyzewska-Khan, Justyna, Rowan, Andrew, Chambers, Tim, Matthews, Nik, Turajlic, Samra, Hiley, Crispin, Lee, Siow Ming, Forster, Martin D., Ahmad, Tanya, Falzon, Mary, Borg, Elaine, Lawrence, David, Hayward, Martin, Kolvekar, Shyam, Panagiotopoulos, Nikolaos, Janes, Sam M, Thakrar, Ricky, Ahmed, Asia, Blackhall, Fiona, Summers, Yvonne, Hafez, Dina, Naik, Ashwini, Ganguly, Apratim, Kareht, Stephanie, Shah, Rajesh, Joseph, Leena, Quinn, Anne Marie, Crosbie, Phil, Naidu, Babu, Middleton, Gary, Langman, Gerald, Trotter, Simon, Nicolson, Marianne, Remmen, Hardy, Kerr, Keith, Chetty, Mahendran, Gomersall, Lesley, Fennell, Dean, Nakas, Apostolos, Rathinam, Sridhar, Anand, Girija, Khan, Sajid, Russell, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-sellers, Melanie, Prakash, Vineet, Lester, Jason, Kornaszewska, Malgorzata, Attanoos, Richard, Adams, Haydn, Davies, Helen, Oukrif, Dahmane, Akarca, Ayse U, Hartley, John A, Lowe, Helen L, Lock, Sara, Iles, Natasha, Bell, Harriet, Ngai, Yenting, Elgar, Greg, Szallasi, Zoltan, Schwarz, Roland F, Herrero, Javier, Stewart, Aengus, Quezada, Sergio A, Peggs, Karl S., Van Loo, Peter, Dive, Caroline, Lin, Jimmy, Rabinowitz, Matthew, Aerts, Hugo JWL, Hackshaw, Allan, Shaw, Jacqui A, Zimmermann, Bernhard G., Swanton, Charles
Published in Nature (2017)