A Novel Metabotropic Glutamate Receptor 5 Positive Allosteric Modulator Acts at a Unique Site and Confers Stimulus Bias to mGlu5 Signaling

af Noetzel, M. J., Gregory, K. J., Vinson, P. N., Manka, J. T., Stauffer, S. R., Lindsley, C. W., Niswender, C. M., Xiang, Z., Conn, P. J.
Udgivet 2013

Role for the M(1) Muscarinic Acetylcholine Receptor in Top-Down Cognitive Processing Using a Touchscreen Visual Discrimination Task in Mice

af Gould, R. W., Dencker, D., Grannan, M., Bubser, M., Zhan, X., Wess, J., Xiang, Z., Locuson, C., Lindsley, C. W., Conn, P. J., Jones, C. K.
Udgivet i ACS Chem Neurosci (2015)

Potentiation of mGlu5 receptors with the novel enhancer, VU0360172, reduces spontaneous absence seizures in WAG/Rij rats

af D’Amore, V., Santolini, I., van Rijn, C.M., Biagioni, F., Molinaro, G., Prete, A., Conn, P.J., Lindsley, C.W., Zhou, Y., Vinson, P.N., Rodriguez, A.L., Jones, C.K., Stauffer, S.R., Nicoletti, F., van Luijtelaar, G., Ngomba, R.T.
Udgivet 2012

Potentiation of M(1) Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model

af Ghoshal, A, Rook, J M, Dickerson, J W, Roop, G N, Morrison, R D, Jalan-Sakrikar, N, Lamsal, A, Noetzel, M J, Poslusney, M S, Wood, M R, Melancon, B J, Stauffer, S R, Xiang, Z, Daniels, J S, Niswender, C M, Jones, C K, Lindsley, C W, Conn, P J
Udgivet i Neuropsychopharmacology (2016)

N-Aryl Piperazine Metabotropic Glutamate Receptor 5 Positive Allosteric Modulators Possess Efficacy in Preclinical Models of NMDA Hypofunction and Cognitive Enhancement

af Gregory, K.J., Herman, E.J., Ramsey, A.J., Hammond, A.S., Byun, N.E., Stauffer, S.R., Manka, J.T., Jadhav, S., Bridges, T.M., Weaver, C.D., Niswender, C.M., Steckler, T., Drinkenburg, W.H., Ahnaou, A., Lavreysen, H., Macdonald, G.J., Bartolomé, J.M., Mackie, C., Hrupka, B.J., Caron, M.G., Daigle, T.L., Lindsley, C.W., Conn, P.J., Jones, C.K.
Udgivet 2013