Protein Phosphatase-1 –targeted Small Molecules, Iron Chelators and Curcumin Analogs as HIV-1 Antivirals

由 Lin, Xionghao, Ammosova, Tatyana, Kumari, Namita, Nekhai, Sergei
發表在 Curr Pharm Des (2017)

Discovery of a Novel HDAC2 Inhibitor by a Scaffold-Merging Hybrid Query

由 Basant, Nikita, Lin, Xionghao, Reid, Terry-Elinor R., Karla, Pradeep K., Wang, Xiang S.
發表在 Comb Chem High Throughput Screen (2015)

Urinary Orosomucoid is Associated with Progressive Chronic Kidney Disease Stage in Patients with Sickle Cell Anemia

由 Jerebtsova, Marina, Saraf, Santosh L., Soni, Simran, Afangbedji, Nowah, Lin, Xionghao, Raslan, Rasha, Gordeuk, Victor R., Nekhai, Sergei
發表在 Am J Hematol (2018)

Protein Phosphatase 1α Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation

由 Carey, Brian D., Ammosova, Tatiana, Pinkham, Chelsea, Lin, Xionghao, Zhou, Weidong, Liotta, Lance A., Nekhai, Sergei, Kehn-Hall, Kylene
發表在 J Virol (2018)

Inhibition of HIV-1 by curcumin A, a novel curcumin analog

由 Kumari, Namita, Kulkarni, Amol A, Lin, Xionghao, McLean, Charlee, Ammosova, Tatiana, Ivanov, Andrey, Hipolito, Maria, Nekhai, Sergei, Nwulia, Evaristus
發表在 Drug Des Devel Ther (2015)

Increased iron export by ferroportin induces restriction of HIV-1 infection in sickle cell disease

由 Kumari, Namita, Ammosova, Tatiana, Diaz, Sharmin, Lin, Xionghao, Niu, Xiaomei, Ivanov, Andrey, Jerebtsova, Marina, Dhawan, Subhash, Oneal, Patricia, Nekhai, Sergei
發表在 Blood Adv (2016)

Phosphorylated VP30 of Marburg Virus Is a Repressor of Transcription

由 Tigabu, Bersabeh, Ramanathan, Palaniappan, Ivanov, Andrey, Lin, Xionghao, Ilinykh, Philipp A., Parry, Christian S., Freiberg, Alexander N., Nekhai, Sergei, Bukreyev, Alexander
發表在 J Virol (2018)

Phenyl-1-Pyridin-2yl-Ethanone-Based Iron Chelators Increase IκB-α Expression, Modulate CDK2 and CDK9 Activities, and Inhibit HIV-1 Transcription

由 Kumari, Namita, Iordanskiy, Sergey, Kovalskyy, Dmytro, Breuer, Denitra, Niu, Xiaomei, Lin, Xionghao, Xu, Min, Gavrilenko, Konstantin, Kashanchi, Fatah, Dhawan, Subhash, Nekhai, Sergei
發表在 Antimicrob Agents Chemother (2014)

HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription

由 Ivanov, Andrey, Lin, Xionghao, Ammosova, Tatiana, Ilatovskiy, Andrey V., Kumari, Namita, Lassiter, Hatajai, Afangbedji, Nowah, Niu, Xiaomei, Petukhov, Michael G., Nekhai, Sergei
發表在 Retrovirology (2018)

Protein Phosphatase 1 Regulates Human Cytomegalovirus Protein Translation by Restraining AMPK Signaling

由 Stecher, Carmen, Marinkov, Sanja, Mayr-Harting, Lucia, Katic, Ana, Kastner, Marie-Theres, Rieder-Rommer, Franz J. J., Lin, Xionghao, Nekhai, Sergei, Steininger, Christoph
發表在 Front Microbiol (2021)

Activation of HIV-1 with Nanoparticle-Packaged Small-Molecule Protein Phosphatase-1-Targeting Compound

由 Smith, Kahli A., Lin, Xionghao, Bolshakov, Oleg, Griffin, James, Niu, Xiaomei, Kovalskyy, Dmytro, Ivanov, Andrey, Jerebtsova, Marina, Taylor, Robert E., Akala, Emmanuel, Nekhai, Sergei
發表在 Sci Pharm (2015)

Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription

由 Ivanov, Andrey, Ramanathan, Palaniappan, Parry, Christian, Ilinykh, Philipp A., Lin, Xionghao, Petukhov, Michael, Obukhov, Yuri, Ammosova, Tatiana, Amarasinghe, Gaya K., Bukreyev, Alexander, Nekhai, Sergei
發表在 Cell Mol Life Sci (2019)

Identification of ceruloplasmin as a biomarker of chronic kidney disease in urine of sickle cell disease patients by proteomic analysis

由 Jerebtsova, Marina, Saraf, Santosh L., Lin, Xionghao, Lee, Gillian, Adjei, Elena Afia, Kumari, Namita, Afangbedji, Nowah, Raslan, Rasha, McLean, Charlee, Gordeuk, Victor R., Nekhai, Sergei
發表在 Am J Hematol (2017)

Protein Phosphatase 1–Targeting Small-Molecule C31 Inhibits Ebola Virus Replication

由 Ammosova, Tatiana, Pietzsch, Colette A, Saygideğer, Yasemin, Ilatovsky, Andrey, Lin, Xionghao, Ivanov, Andrey, Kumari, Namita, Jerebtsova, Marina, Kulkarni, Amol, Petukhov, Michael, Üren, Aykut, Bukreyev, Alexander, Nekhai, Sergei
發表在 J Infect Dis (2018)

Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

由 Lin, Xionghao, Ammosova, Tatiana, Choy, Meng S., Pietzsch, Colette A., Ivanov, Andrey, Ahmad, Asrar, Saygideğer, Yasemin, Kumari, Namita, Kovalskyy, Dmytro, Üren, Aykut, Peti, Wolfgang, Bukreyev, Alexander, Nekhai, Sergei
發表在 Front Microbiol (2019)

Structural Optimization of 2,3-Dihydro-1H-cyclopenta[b]quinolines Targeting the Noncatalytic RVxF Site of Protein Phosphatase 1 for HIV-1 Inhibition

由 Lin, Xionghao, Sajith, Ayyiliath M, Wang, Songping, Kumari, Namita, Choy, Meng S, Ahmad, Asrar, Cadet, Dana R., Gu, Xinbin, Ivanov, Andrey I., Peti, Wolfgang, Kulkarni, Amol, Nekhai, Sergei
發表在 ACS Infect Dis (2020)

Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03

由 Lin, Xionghao, Kumari, Namita, DeMarino, Catherine, Kont, Yasemin Saygideğer, Ammosova, Tatiana, Kulkarni, Amol, Jerebtsova, Marina, Vazquez-Meves, Guelaguetza, Ivanov, Andrey, Dmytro, Kovalskyy, Üren, Aykut, Kashanchi, Fatah, Nekhai, Sergei
發表在 Oncotarget (2017)