Protein Phosphatase-1 –targeted Small Molecules, Iron Chelators and Curcumin Analogs as HIV-1 Antivirals

od Lin, Xionghao, Ammosova, Tatyana, Kumari, Namita, Nekhai, Sergei
izdano v Curr Pharm Des (2017)

Discovery of a Novel HDAC2 Inhibitor by a Scaffold-Merging Hybrid Query

od Basant, Nikita, Lin, Xionghao, Reid, Terry-Elinor R., Karla, Pradeep K., Wang, Xiang S.
izdano v Comb Chem High Throughput Screen (2015)

Urinary Orosomucoid is Associated with Progressive Chronic Kidney Disease Stage in Patients with Sickle Cell Anemia

od Jerebtsova, Marina, Saraf, Santosh L., Soni, Simran, Afangbedji, Nowah, Lin, Xionghao, Raslan, Rasha, Gordeuk, Victor R., Nekhai, Sergei
izdano v Am J Hematol (2018)

Protein Phosphatase 1α Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation

od Carey, Brian D., Ammosova, Tatiana, Pinkham, Chelsea, Lin, Xionghao, Zhou, Weidong, Liotta, Lance A., Nekhai, Sergei, Kehn-Hall, Kylene
izdano v J Virol (2018)

Inhibition of HIV-1 by curcumin A, a novel curcumin analog

od Kumari, Namita, Kulkarni, Amol A, Lin, Xionghao, McLean, Charlee, Ammosova, Tatiana, Ivanov, Andrey, Hipolito, Maria, Nekhai, Sergei, Nwulia, Evaristus
izdano v Drug Des Devel Ther (2015)

Increased iron export by ferroportin induces restriction of HIV-1 infection in sickle cell disease

od Kumari, Namita, Ammosova, Tatiana, Diaz, Sharmin, Lin, Xionghao, Niu, Xiaomei, Ivanov, Andrey, Jerebtsova, Marina, Dhawan, Subhash, Oneal, Patricia, Nekhai, Sergei
izdano v Blood Adv (2016)

Phosphorylated VP30 of Marburg Virus Is a Repressor of Transcription

od Tigabu, Bersabeh, Ramanathan, Palaniappan, Ivanov, Andrey, Lin, Xionghao, Ilinykh, Philipp A., Parry, Christian S., Freiberg, Alexander N., Nekhai, Sergei, Bukreyev, Alexander
izdano v J Virol (2018)

Phenyl-1-Pyridin-2yl-Ethanone-Based Iron Chelators Increase IκB-α Expression, Modulate CDK2 and CDK9 Activities, and Inhibit HIV-1 Transcription

od Kumari, Namita, Iordanskiy, Sergey, Kovalskyy, Dmytro, Breuer, Denitra, Niu, Xiaomei, Lin, Xionghao, Xu, Min, Gavrilenko, Konstantin, Kashanchi, Fatah, Dhawan, Subhash, Nekhai, Sergei
izdano v Antimicrob Agents Chemother (2014)

HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription

od Ivanov, Andrey, Lin, Xionghao, Ammosova, Tatiana, Ilatovskiy, Andrey V., Kumari, Namita, Lassiter, Hatajai, Afangbedji, Nowah, Niu, Xiaomei, Petukhov, Michael G., Nekhai, Sergei
izdano v Retrovirology (2018)

Protein Phosphatase 1 Regulates Human Cytomegalovirus Protein Translation by Restraining AMPK Signaling

od Stecher, Carmen, Marinkov, Sanja, Mayr-Harting, Lucia, Katic, Ana, Kastner, Marie-Theres, Rieder-Rommer, Franz J. J., Lin, Xionghao, Nekhai, Sergei, Steininger, Christoph
izdano v Front Microbiol (2021)

Activation of HIV-1 with Nanoparticle-Packaged Small-Molecule Protein Phosphatase-1-Targeting Compound

od Smith, Kahli A., Lin, Xionghao, Bolshakov, Oleg, Griffin, James, Niu, Xiaomei, Kovalskyy, Dmytro, Ivanov, Andrey, Jerebtsova, Marina, Taylor, Robert E., Akala, Emmanuel, Nekhai, Sergei
izdano v Sci Pharm (2015)

Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription

od Ivanov, Andrey, Ramanathan, Palaniappan, Parry, Christian, Ilinykh, Philipp A., Lin, Xionghao, Petukhov, Michael, Obukhov, Yuri, Ammosova, Tatiana, Amarasinghe, Gaya K., Bukreyev, Alexander, Nekhai, Sergei
izdano v Cell Mol Life Sci (2019)

Identification of ceruloplasmin as a biomarker of chronic kidney disease in urine of sickle cell disease patients by proteomic analysis

od Jerebtsova, Marina, Saraf, Santosh L., Lin, Xionghao, Lee, Gillian, Adjei, Elena Afia, Kumari, Namita, Afangbedji, Nowah, Raslan, Rasha, McLean, Charlee, Gordeuk, Victor R., Nekhai, Sergei
izdano v Am J Hematol (2017)

Protein Phosphatase 1–Targeting Small-Molecule C31 Inhibits Ebola Virus Replication

od Ammosova, Tatiana, Pietzsch, Colette A, Saygideğer, Yasemin, Ilatovsky, Andrey, Lin, Xionghao, Ivanov, Andrey, Kumari, Namita, Jerebtsova, Marina, Kulkarni, Amol, Petukhov, Michael, Üren, Aykut, Bukreyev, Alexander, Nekhai, Sergei
izdano v J Infect Dis (2018)

Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

od Lin, Xionghao, Ammosova, Tatiana, Choy, Meng S., Pietzsch, Colette A., Ivanov, Andrey, Ahmad, Asrar, Saygideğer, Yasemin, Kumari, Namita, Kovalskyy, Dmytro, Üren, Aykut, Peti, Wolfgang, Bukreyev, Alexander, Nekhai, Sergei
izdano v Front Microbiol (2019)

Structural Optimization of 2,3-Dihydro-1H-cyclopenta[b]quinolines Targeting the Noncatalytic RVxF Site of Protein Phosphatase 1 for HIV-1 Inhibition

od Lin, Xionghao, Sajith, Ayyiliath M, Wang, Songping, Kumari, Namita, Choy, Meng S, Ahmad, Asrar, Cadet, Dana R., Gu, Xinbin, Ivanov, Andrey I., Peti, Wolfgang, Kulkarni, Amol, Nekhai, Sergei
izdano v ACS Infect Dis (2020)

Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03

od Lin, Xionghao, Kumari, Namita, DeMarino, Catherine, Kont, Yasemin Saygideğer, Ammosova, Tatiana, Kulkarni, Amol, Jerebtsova, Marina, Vazquez-Meves, Guelaguetza, Ivanov, Andrey, Dmytro, Kovalskyy, Üren, Aykut, Kashanchi, Fatah, Nekhai, Sergei
izdano v Oncotarget (2017)