Protein Phosphatase-1 –targeted Small Molecules, Iron Chelators and Curcumin Analogs as HIV-1 Antivirals

بواسطة Lin, Xionghao, Ammosova, Tatyana, Kumari, Namita, Nekhai, Sergei
الحاوية / القاعدة Curr Pharm Des (2017)

Discovery of a Novel HDAC2 Inhibitor by a Scaffold-Merging Hybrid Query

بواسطة Basant, Nikita, Lin, Xionghao, Reid, Terry-Elinor R., Karla, Pradeep K., Wang, Xiang S.
الحاوية / القاعدة Comb Chem High Throughput Screen (2015)

Urinary Orosomucoid is Associated with Progressive Chronic Kidney Disease Stage in Patients with Sickle Cell Anemia

بواسطة Jerebtsova, Marina, Saraf, Santosh L., Soni, Simran, Afangbedji, Nowah, Lin, Xionghao, Raslan, Rasha, Gordeuk, Victor R., Nekhai, Sergei
الحاوية / القاعدة Am J Hematol (2018)

Protein Phosphatase 1α Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation

بواسطة Carey, Brian D., Ammosova, Tatiana, Pinkham, Chelsea, Lin, Xionghao, Zhou, Weidong, Liotta, Lance A., Nekhai, Sergei, Kehn-Hall, Kylene
الحاوية / القاعدة J Virol (2018)

Inhibition of HIV-1 by curcumin A, a novel curcumin analog

بواسطة Kumari, Namita, Kulkarni, Amol A, Lin, Xionghao, McLean, Charlee, Ammosova, Tatiana, Ivanov, Andrey, Hipolito, Maria, Nekhai, Sergei, Nwulia, Evaristus
الحاوية / القاعدة Drug Des Devel Ther (2015)

Increased iron export by ferroportin induces restriction of HIV-1 infection in sickle cell disease

بواسطة Kumari, Namita, Ammosova, Tatiana, Diaz, Sharmin, Lin, Xionghao, Niu, Xiaomei, Ivanov, Andrey, Jerebtsova, Marina, Dhawan, Subhash, Oneal, Patricia, Nekhai, Sergei
الحاوية / القاعدة Blood Adv (2016)

Phosphorylated VP30 of Marburg Virus Is a Repressor of Transcription

بواسطة Tigabu, Bersabeh, Ramanathan, Palaniappan, Ivanov, Andrey, Lin, Xionghao, Ilinykh, Philipp A., Parry, Christian S., Freiberg, Alexander N., Nekhai, Sergei, Bukreyev, Alexander
الحاوية / القاعدة J Virol (2018)

Phenyl-1-Pyridin-2yl-Ethanone-Based Iron Chelators Increase IκB-α Expression, Modulate CDK2 and CDK9 Activities, and Inhibit HIV-1 Transcription

بواسطة Kumari, Namita, Iordanskiy, Sergey, Kovalskyy, Dmytro, Breuer, Denitra, Niu, Xiaomei, Lin, Xionghao, Xu, Min, Gavrilenko, Konstantin, Kashanchi, Fatah, Dhawan, Subhash, Nekhai, Sergei
الحاوية / القاعدة Antimicrob Agents Chemother (2014)

HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription

بواسطة Ivanov, Andrey, Lin, Xionghao, Ammosova, Tatiana, Ilatovskiy, Andrey V., Kumari, Namita, Lassiter, Hatajai, Afangbedji, Nowah, Niu, Xiaomei, Petukhov, Michael G., Nekhai, Sergei
الحاوية / القاعدة Retrovirology (2018)

Protein Phosphatase 1 Regulates Human Cytomegalovirus Protein Translation by Restraining AMPK Signaling

بواسطة Stecher, Carmen, Marinkov, Sanja, Mayr-Harting, Lucia, Katic, Ana, Kastner, Marie-Theres, Rieder-Rommer, Franz J. J., Lin, Xionghao, Nekhai, Sergei, Steininger, Christoph
الحاوية / القاعدة Front Microbiol (2021)

Activation of HIV-1 with Nanoparticle-Packaged Small-Molecule Protein Phosphatase-1-Targeting Compound

بواسطة Smith, Kahli A., Lin, Xionghao, Bolshakov, Oleg, Griffin, James, Niu, Xiaomei, Kovalskyy, Dmytro, Ivanov, Andrey, Jerebtsova, Marina, Taylor, Robert E., Akala, Emmanuel, Nekhai, Sergei
الحاوية / القاعدة Sci Pharm (2015)

Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription

بواسطة Ivanov, Andrey, Ramanathan, Palaniappan, Parry, Christian, Ilinykh, Philipp A., Lin, Xionghao, Petukhov, Michael, Obukhov, Yuri, Ammosova, Tatiana, Amarasinghe, Gaya K., Bukreyev, Alexander, Nekhai, Sergei
الحاوية / القاعدة Cell Mol Life Sci (2019)

Identification of ceruloplasmin as a biomarker of chronic kidney disease in urine of sickle cell disease patients by proteomic analysis

بواسطة Jerebtsova, Marina, Saraf, Santosh L., Lin, Xionghao, Lee, Gillian, Adjei, Elena Afia, Kumari, Namita, Afangbedji, Nowah, Raslan, Rasha, McLean, Charlee, Gordeuk, Victor R., Nekhai, Sergei
الحاوية / القاعدة Am J Hematol (2017)

Protein Phosphatase 1–Targeting Small-Molecule C31 Inhibits Ebola Virus Replication

بواسطة Ammosova, Tatiana, Pietzsch, Colette A, Saygideğer, Yasemin, Ilatovsky, Andrey, Lin, Xionghao, Ivanov, Andrey, Kumari, Namita, Jerebtsova, Marina, Kulkarni, Amol, Petukhov, Michael, Üren, Aykut, Bukreyev, Alexander, Nekhai, Sergei
الحاوية / القاعدة J Infect Dis (2018)

Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

بواسطة Lin, Xionghao, Ammosova, Tatiana, Choy, Meng S., Pietzsch, Colette A., Ivanov, Andrey, Ahmad, Asrar, Saygideğer, Yasemin, Kumari, Namita, Kovalskyy, Dmytro, Üren, Aykut, Peti, Wolfgang, Bukreyev, Alexander, Nekhai, Sergei
الحاوية / القاعدة Front Microbiol (2019)

Structural Optimization of 2,3-Dihydro-1H-cyclopenta[b]quinolines Targeting the Noncatalytic RVxF Site of Protein Phosphatase 1 for HIV-1 Inhibition

بواسطة Lin, Xionghao, Sajith, Ayyiliath M, Wang, Songping, Kumari, Namita, Choy, Meng S, Ahmad, Asrar, Cadet, Dana R., Gu, Xinbin, Ivanov, Andrey I., Peti, Wolfgang, Kulkarni, Amol, Nekhai, Sergei
الحاوية / القاعدة ACS Infect Dis (2020)

Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03

بواسطة Lin, Xionghao, Kumari, Namita, DeMarino, Catherine, Kont, Yasemin Saygideğer, Ammosova, Tatiana, Kulkarni, Amol, Jerebtsova, Marina, Vazquez-Meves, Guelaguetza, Ivanov, Andrey, Dmytro, Kovalskyy, Üren, Aykut, Kashanchi, Fatah, Nekhai, Sergei
الحاوية / القاعدة Oncotarget (2017)