A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches

Por Stiborová, Marie, Bárta, František, Levová, Kateřina, Hodek, Petr, Schmeiser, Heinz H., Arlt, Volker M., Martínek, Václav
Publicado no Int J Mol Sci (2015)

Bioactivation versus Detoxication of the Urothelial Carcinogen Aristolochic Acid I by Human Cytochrome P450 1A1 and 1A2

Por Stiborová, Marie, Levová, Kateřina, Bárta, František, Shi, Zhanquan, Frei, Eva, Schmeiser, Heinz H., Nebert, Daniel W., Phillips, David H., Arlt, Volker M.
Publicado em 2012

Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo

Por Dračínská, Helena, Bárta, František, Levová, Kateřina, Hudecová, Alena, Moserová, Michaela, Schmeiser, Heinz H., Kopka, Klaus, Frei, Eva, Arlt, Volker M., Stiborová, Marie
Publicado no Toxicology (2016)