HPV8 early genes modulate differentiation and cell cycle of primary human adult keratinocytes

per Akgül, Baki, Ghali, Lucy, Davies, Derek, Pfister, Herbert, Leigh, Irene M., Storey, Alan
Publicat 2007

Two Mechanisms Regulate Keratin K15 Expression In Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signalling

per Bose, Amrita, Teh, Muy-Teck, Hutchison, Iain L., Wan, Hong, Leigh, Irene M., Waseem, Ahmad
Publicat 2012

Expression of Keratin K2e in Cutaneous and Oral Lesions : Association with Keratinocyte Activation, Proliferation, and Keratinization

per Bloor, Balvinder K., Tidman, Nicholas, Leigh, Irene M., Odell, Edward, Dogan, Bilal, Wollina, Uwe, Ghali, Lucy, Waseem, Ahmad
Publicat 2003

Missense Mutations in Fumarate Hydratase in Multiple Cutaneous and Uterine Leiomyomatosis and Renal Cell Cancer

per Alam, N. Afrina, Olpin, Simon, Rowan, Andrew, Kelsell, David, Leigh, Irene M., Tomlinson, Ian P. M., Weaver, Todd
Publicat 2005

Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity

per Hepburn, Lydia A., McHugh, Angela, Fernandes, Kenneth, Boag, Garry, Proby, Charlotte M., Leigh, Irene M., Saville, Mark K.
Publicat a Oncotarget (2018)

Phosphorylated Human Keratinocyte Ornithine Decarboxylase Is Preferentially Associated with Insoluble Cellular Proteins

per Pomidor, Mary M., Cimildoro, Rebecca, Lazatin, Bien, Zheng, Ping, Gurr, James A., Leigh, Irene M., Jänne, Olli A., Tuan, Rocky S., Hickok, Noreen J.
Publicat 1999

Degenerate and Nested PCR: a Highly Sensitive and Specific Method for Detection of Human Papillomavirus Infection in Cutaneous Warts

per Harwood, Catherine A., Spink, Patricia J., Surentheran, T., Leigh, Irene M., de Villiers, Ethel-Michele, McGregor, Jane M., Proby, Charlotte M., Breuer, Judith
Publicat 1999

Tyrosine dephosphorylation is required for Bak activation in apoptosis

per Fox, Joanna L, Ismail, Ferina, Azad, Abul, Ternette, Nicola, Leverrier, Sabrina, Edelmann, Mariola J, Kessler, Benedikt M, Leigh, Irene M, Jackson, Sarah, Storey, Alan
Publicat 2010

Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity

per McHugh, Angela, Fernandes, Kenneth, South, Andrew P., Mellerio, Jemima E., Salas-Alanís, Julio C., Proby, Charlotte M., Leigh, Irene M., Saville, Mark K.
Publicat a Oncotarget (2018)

Binding of Integrin α6β4 to Plectin Prevents Plectin Association with F-Actin but Does Not Interfere with Intermediate Filament Binding

per Geerts, Dirk, Fontao, Lionel, Nievers, Mirjam G., Schaapveld, Roel Q.J., Purkis, Patricia E., Wheeler, Grant N., Lane, E. Birgitte, Leigh, Irene M., Sonnenberg, Arnoud
Publicat 1999

The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma

per McHugh, Angela, Fernandes, Kenneth, Chinner, Nerime, Ibrahim, Adel F.M., Garg, Amit K., Boag, Garry, Hepburn, Lydia A., Proby, Charlotte M., Leigh, Irene M., Saville, Mark K.
Publicat a J Invest Dermatol (2020)

The Genomic Landscape of Actinic Keratosis

per Thomson, Jason, Bewicke-Copley, Findlay, Anene, Chinedu Anthony, Gulati, Abha, Nagano, Ai, Purdie, Karin, Inman, Gareth J., Proby, Charlotte M., Leigh, Irene M., Harwood, Catherine A., Wang, Jun
Publicat a J Invest Dermatol (2021)

Single Nucleotide Polymorphism Array Analysis Defines a Specific Genetic Fingerprint for Well-Differentiated Cutaneous SCCs

per Purdie, Karin J., Harwood, Catherine A., Gulati, Abha, Chaplin, Tracy, Lambert, Sally R., Cerio, Rino, Kelly, Gavin, Cazier, Jean Baptiste, Young, Bryan D., Leigh, Irene M., Proby, Charlotte M.
Publicat 2009

Genomic analysis of atypical fibroxanthoma

per Lai, Kevin, Harwood, Catherine A., Purdie, Karin J., Proby, Charlotte M., Leigh, Irene M., Ravi, Namita, Mully, Thaddeus W., Brooks, Lionel, Sandoval, Priscilla M., Rosenblum, Michael D., Arron, Sarah T.
Publicat a PLoS One (2017)

Nationwide Incidence of Metastatic Cutaneous Squamous Cell Carcinoma in England

per Venables, Zoë C., Autier, Philippe, Nijsten, Tamar, Wong, Kwok F., Langan, Sinéad M., Rous, Brian, Broggio, John, Harwood, Catherine, Henson, Katherine, Proby, Charlotte M., Rashbass, Jem, Leigh, Irene M.
Publicat a JAMA Dermatol (2018)

Allelic Imbalances and Microdeletions Affecting the PTPRD Gene in Cutaneous Squamous Cell Carcinomas Detected Using Single Nucleotide Polymorphism Microarray Analysis

per Purdie, Karin J., Lambert, Sally R., Teh, Muy-Teck, Chaplin, Tracy, Molloy, Gael, Raghavan, Manoj, Kelsell, David P., Leigh, Irene M., Harwood, Catherine A., Proby, Charlotte M., Young, Bryan D.
Publicat 2007

Growth and Viability of Cutaneous Squamous Cell Carcinoma Cell Lines Display Different Sensitivities to Isoform-Specific Phosphoinositide 3-Kinase Inhibitors

per Mannella, Viviana, Boehm, Kira, Celik, Suheyla, Ali, Tasnim, Mirza, Amnah N., El Hasnaouy, Mariam, Kaffa, Andreas, Lyu, Yanshuang, Kafaei Golahmadi, Donya, Leigh, Irene M., Bergamaschi, Daniele, Harwood, Catherine A., Maffucci, Tania
Publicat a Int J Mol Sci (2021)

Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16

per Maruthappu, Thiviyani, Chikh, Anissa, Fell, Benjamin, Delaney, Paul J., Brooke, Matthew A., Levet, Clemence, Moncada-Pazos, Angela, Ishida-Yamamoto, Akemi, Blaydon, Diana, Waseem, Ahmad, Leigh, Irene M., Freeman, Matthew, Kelsell, David P.
Publicat a Nat Commun (2017)

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions

per Purdie, Karin J., Proby, Charlotte M., Rizvi, Hasan, Griffin, Heather, Doorbar, John, Sommerlad, Mary, Feltkamp, Mariet C., der Meijden, Els Van, Inman, Gareth J., South, Andrew P., Leigh, Irene M., Harwood, Catherine A.
Publicat a Front Microbiol (2018)

Intermediate filament–membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength

per Huen, Arthur C., Park, Jung K., Godsel, Lisa M., Chen, Xuejun, Bannon, Leslie J., Amargo, Evangeline V., Hudson, Tracie Y., Mongiu, Anne K., Leigh, Irene M., Kelsell, David P., Gumbiner, Barry M., Green, Kathleen J.
Publicat 2002