Airway hyperresponsiveness; smooth muscle as the principal actor

Por Lauzon, Anne-Marie, Martin, James G.
Publicado no F1000Res (2016)

Accumulating Evidence for Increased Velocity of Airway Smooth Muscle Shortening in Asthmatic Airway Hyperresponsiveness

Por Ijpma, Gijs, Matusovsky, Oleg, Lauzon, Anne-Marie
Publicado em 2012

Spreading of perturbations in myosin group kinetics along actin filaments

Por Balassy, Zsombor, Lauzon, Anne-Marie, Hilbert, Lennart
Publicado no Proc Natl Acad Sci U S A (2019)

Affinity for MgADP and force of unbinding from actin of myosin purified from tonic and phasic smooth muscle

Por Léguillette, Renaud, Zitouni, Nedjma B., Govindaraju, Karuthapillai, Fong, Laura M., Lauzon, Anne-Marie
Publicado em 2008

The Kinetics of Mechanically Coupled Myosins Exhibit Group Size-Dependent Regimes

Por Hilbert, Lennart, Cumarasamy, Shivaram, Zitouni, Nedjma B., Mackey, Michael C., Lauzon, Anne-Marie
Publicado em 2013

CD4(+) T cells enhance the unloaded shortening velocity of airway smooth muscle by altering the contractile protein expression

Por Matusovsky, Oleg S, Nakada, Emily M, Kachmar, Linda, Fixman, Elizabeth D, Lauzon, Anne-Marie
Publicado em 2014

Phosphate and ADP Differently Inhibit Coordinated Smooth Muscle Myosin Groups

Por Hilbert, Lennart, Balassy, Zsombor, Zitouni, Nedjma B., Mackey, Michael C., Lauzon, Anne-Marie
Publicado no Biophys J (2015)

A Multi-Scale Approach to Airway Hyperresponsiveness: From Molecule to Organ

Por Lauzon, Anne-Marie, Bates, Jason H. T., Donovan, Graham, Tawhai, Merryn, Sneyd, James, Sanderson, Michael J.
Publicado em 2012

The Role of Caldesmon and its Phosphorylation by ERK on the Binding Force of Unphosphorylated Myosin to Actin

Por Roman, Horia Nicolae, Zitouni, Nedjma B., Kachmar, Linda, Benedetti, Andrea, Sobieszek, Apolinary, Lauzon, Anne-Marie
Publicado em 2014

Human Trachealis and Main Bronchi Smooth Muscle Are Normoresponsive in Asthma

Por Ijpma, Gijs, Kachmar, Linda, Matusovsky, Oleg S., Bates, Jason H. T., Benedetti, Andrea, Martin, James G., Lauzon, Anne-Marie
Publicado no Am J Respir Crit Care Med (2015)

Caffeine relaxes smooth muscle through actin depolymerization

Por Tazzeo, Tracy, Bates, Genevieve, Roman, Horia Nicolae, Lauzon, Anne-Marie, Khasnis, Mukta D., Eto, Masumi, Janssen, Luke J.
Publicado em 2012

Peripheral Airway Smooth Muscle, but Not the Trachealis, Is Hypercontractile in an Equine Model of Asthma

Por Matusovsky, Oleg S., Kachmar, Linda, Ijpma, Gijs, Bates, Genevieve, Zitouni, Nedjma, Benedetti, Andrea, Lavoie, Jean-Pierre, Lauzon, Anne-Marie
Publicado no Am J Respir Cell Mol Biol (2016)

Myosin, Transgelin, and Myosin Light Chain Kinase: Expression and Function in Asthma

Por Léguillette, Renaud, Laviolette, Michel, Bergeron, Celine, Zitouni, Nedjma, Kogut, Paul, Solway, Julian, Kachmar, Linda, Hamid, Qutayba, Lauzon, Anne-Marie
Publicado em 2009

Could an increase in airway smooth muscle shortening velocity cause airway hyperresponsiveness?

Por Bullimore, Sharon R., Siddiqui, Sana, Donovan, Graham M., Martin, James G., Sneyd, James, Bates, Jason H. T., Lauzon, Anne-Marie
Publicado em 2011

Myosin conformational states determined by single fluorophore polarization

Por Warshaw, David M., Hayes, Eric, Gaffney, Donald, Lauzon, Anne-Marie, Wu, Junru, Kennedy, Guy, Trybus, Kathleen, Lowey, Susan, Berger, Christopher
Publicado em 1998

A multiscale, spatially-distributed model of asthmatic airway hyper-responsiveness

Por Politi, Antonio Z., Donovan, Graham M., Tawhai, Merryn H., Sanderson, Michael J., Lauzon, Anne-Marie, Bates, Jason H. T., Sneyd, James
Publicado em 2010

A Continuous-Binding Cross-Linker Model for Passive Airway Smooth Muscle

Por Donovan, Graham M., Bullimore, Sharon R., Elvin, Amanda J., Tawhai, Merryn H., Bates, Jason H.T., Lauzon, Anne-Marie, Sneyd, James
Publicado em 2010

Unphosphorylated calponin enhances the binding force of unphosphorylated myosin to actin

Por Roman, Horia Nicolae, Zitouni, Nedjma B., Kachmar, Linda, Ijpma, Gijs, Hilbert, Lennart, Matusovskiy, Oleg, Benedetti, Andrea, Sobieszek, Apolinary, Lauzon, Anne-Marie
Publicado em 2013

Molecular Mechanical Differences between Isoforms of Contractile Actin in the Presence of Isoforms of Smooth Muscle Tropomyosin

Por Hilbert, Lennart, Bates, Genevieve, Roman, Horia N., Blumenthal, Jenna L., Zitouni, Nedjma B., Sobieszek, Apolinary, Mackey, Michael C., Lauzon, Anne-Marie
Publicado em 2013

Epithelial Cells Induce a Cyclo-Oxygenase-1–Dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype

Por O’Sullivan, Michael J., Gabriel, Elizabeth, Panariti, Alice, Park, Chan Y., Ijpma, Gijs, Fredberg, Jeffrey J., Lauzon, Anne-Marie, Martin, James G.
Publicado no Am J Respir Cell Mol Biol (2017)