Epithelial Cells Induce a Cyclo-Oxygenase-1–Dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype

Airway smooth muscle cells (ASMCs) are phenotypically regulated to exist in either a proliferative or a contractile state. However, the influence of other airway structural cell types on ASMC phenotype is largely unknown. Although epithelial cells are known to drive ASM proliferation, their effects...

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Pubblicato in:Am J Respir Cell Mol Biol
Autori principali: O’Sullivan, Michael J., Gabriel, Elizabeth, Panariti, Alice, Park, Chan Y., Ijpma, Gijs, Fredberg, Jeffrey J., Lauzon, Anne-Marie, Martin, James G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2017
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765417/
https://ncbi.nlm.nih.gov/pubmed/28708434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0427OC
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