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Human Trachealis and Main Bronchi Smooth Muscle Are Normoresponsive in Asthma

Rationale: Airway smooth muscle (ASM) plays a key role in airway hyperresponsiveness (AHR) but it is unclear whether its contractility is intrinsically changed in asthma. Objectives: To investigate whether key parameters of ASM contractility are altered in subjects with asthma. Methods: Human trache...

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Détails bibliographiques
Publié dans:Am J Respir Crit Care Med
Auteurs principaux: Ijpma, Gijs, Kachmar, Linda, Matusovsky, Oleg S., Bates, Jason H. T., Benedetti, Andrea, Martin, James G., Lauzon, Anne-Marie
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435453/
https://ncbi.nlm.nih.gov/pubmed/25695616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201407-1296OC
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