Characterization of two independent mechanisms by which interferon-induced gene expression is down regulated.

Por Akai, H, Larner, A C
Publicado em 1990

In vitro activation of the transcription factor gamma interferon activation factor by gamma interferon: evidence for a tyrosine phosphatase/kinase signaling cascade.

Por Igarashi, K, David, M, Finbloom, D S, Larner, A C
Publicado em 1993

In vitro activation of a transcription factor by gamma interferon requires a membrane-associated tyrosine kinase and is mimicked by vanadate.

Por Igarashi, K, David, M, Larner, A C, Finbloom, D S
Publicado em 1993

A nuclear tyrosine phosphatase downregulates interferon-induced gene expression.

Por David, M, Grimley, P M, Finbloom, D S, Larner, A C
Publicado em 1993

Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1.

Por David, M, Chen, H E, Goelz, S, Larner, A C, Neel, B G
Publicado em 1995

Human cancer cell lines express a negative transcriptional regulator of the interferon regulatory factor family of DNA binding proteins.

Por Petricoin, E, David, M, Fang, H, Grimley, P, Larner, A C, Vande Pol, S
Publicado em 1994

Transcriptional induction of two genes in human cells by beta interferon.

Por Larner, A C, Jonak, G, Cheng, Y S, Korant, B, Knight, E, Darnell, J E
Publicado em 1984

Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation.

Por David, M, Petricoin, E F, Igarashi, K, Feldman, G M, Finbloom, D S, Larner, A C
Publicado em 1994

Modulation of interferon signaling in human fibroblasts by phorbol esters.

Por Petricoin, E F, Hackett, R H, Akai, H, Igarashi, K, Finbloom, D S, Larner, A C
Publicado em 1992

Inhibition of alpha interferon but not gamma interferon signal transduction by phorbol esters is mediated by a tyrosine phosphatase.

Por Petricoin, E, David, M, Igarashi, K, Benjamin, C, Ling, L, Goelz, S, Finbloom, D S, Larner, A C
Publicado em 1996

Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes.

Por Bacon, C M, Petricoin, E F, Ortaldo, J R, Rees, R C, Larner, A C, Johnston, J A, O'Shea, J J
Publicado em 1995

Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway.

Por Stancato, L F, Sakatsume, M, David, M, Dent, P, Dong, F, Petricoin, E F, Krolewski, J J, Silvennoinen, O, Saharinen, P, Pierce, J, Marshall, C J, Sturgill, T, Finbloom, D S, Larner, A C
Publicado em 1997