Meta-fibrosis links positive energy balance and mitochondrial metabolism to insulin resistance

Por Lark, Daniel S., Wasserman, David H.
Publicado no F1000Res (2017)

Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers

Por Lark, Daniel S., Torres, Maria J., Lin, Chien-Te, Ryan, Terence E., Anderson, Ethan J., Neufer, P. Darrell
Publicado no Am J Physiol Cell Physiol (2016)

Enhanced Mitochondrial Superoxide Scavenging Does Not Improve Muscle Insulin Action in the High Fat-Fed Mouse

Por Lark, Daniel S., Kang, Li, Lustig, Mary E., Bonner, Jeffrey S., James, Freyja D., Neufer, P. Darrell, Wasserman, David H.
Publicado no PLoS One (2015)

Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H(2)O(2) emitting source under conditions of nutrient overload

Por Fisher-Wellman, Kelsey H., Gilliam, Laura A. A., Lin, Chien-Te, Cathey, Brook L., Lark, Daniel S., Neufer, P. Darrell
Publicado em 2013

Protein Kinase A Governs Oxidative Phosphorylation Kinetics and Oxidant Emitting Potential at Complex I

Por Lark, Daniel S., Reese, Lauren R., Ryan, Terence E., Torres, Maria J., Smith, Cody D., Lin, Chien-Te, Neufer, P. Darrell
Publicado no Front Physiol (2015)

Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction

Por Gilliam, Laura A. A., Lark, Daniel S., Reese, Lauren R., Torres, Maria J., Ryan, Terence E., Lin, Chien-Te, Cathey, Brook L., Neufer, P. Darrell
Publicado no Am J Physiol Endocrinol Metab (2016)

Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy

Por Litt, Michael J, Okoye, G Donald, Lark, Daniel, Cakir, Isin, Moore, Christy, Barber, Mary C, Atkinson, James, Fessel, Josh, Moslehi, Javid, Cone, Roger D
Publicado no eLife (2017)

Reduced Nonexercise Activity Attenuates Negative Energy Balance in Mice Engaged in Voluntary Exercise

Por Lark, Daniel S., Kwan, Jamie R., McClatchey, P. Mason, James, Merrygay N., James, Freyja D., Lighton, John R.B., Lantier, Louise, Wasserman, David H.
Publicado no Diabetes (2018)

Do Fish Oil Omega-3 Fatty Acids Enhance Antioxidant Capacity and Mitochondrial Fatty Acid Oxidation in Human Atrial Myocardium via PPARγ Activation?

Por Anderson, Ethan J., Thayne, Kathleen A., Harris, Mitchel, Shaikh, Saame Raza, Darden, Timothy M., Lark, Daniel S., Williams, John Mark, Chitwood, W. Randolph, Kypson, Alan P., Rodriguez, Evelio
Publicado em 2014

Integrin-Linked Kinase in Muscle Is Necessary for the Development of Insulin Resistance in Diet-Induced Obese Mice

Por Kang, Li, Mokshagundam, Shilpa, Reuter, Bradley, Lark, Daniel S., Sneddon, Claire C., Hennayake, Chandani, Williams, Ashley S., Bracy, Deanna P., James, Freyja D., Pozzi, Ambra, Zent, Roy, Wasserman, David H.
Publicado no Diabetes (2016)

Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle

Por Perry, Christopher G R, Kane, Daniel A, Herbst, Eric A F, Mukai, Kazutaka, Lark, Daniel S, Wright, David C, Heigenhauser, George J F, Neufer, P Darrell, Spriet, Lawrence L, Holloway, Graham P
Publicado em 2012

Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy consuming redox circuit

Por Fisher-Wellman, Kelsey H., Lin, Chien-Te, Ryan, Terence E., Reese, Lauren R., Gilliam, Laura A. A., Cathey, Brook L., Lark, Daniel S., Smith, Cody D., Muoio, Deborah M., Neufer, P. Darrell
Publicado no Biochem J (2015)

Inhibiting Myosin-ATPase Reveals Dynamic Range of Mitochondrial Respiratory Control in Skeletal Muscle

Por Perry, Christopher G.R., Kane, Daniel A., Lin, Chien-Te, Kozy, Rachel, Cathey, Brook L., Lark, Daniel S., Kane, Constance L., Brophy, Patricia M., Gavin, Timothy P, Anderson, Ethan J., Neufer, P. Darrell
Publicado em 2011

Targeted Metabolomics Connects Thioredoxin-interacting Protein (TXNIP) to Mitochondrial Fuel Selection and Regulation of Specific Oxidoreductase Enzymes in Skeletal Muscle

Por DeBalsi, Karen L., Wong, Kari E., Koves, Timothy R., Slentz, Dorothy H., Seiler, Sarah E., Wittmann, April H., Ilkayeva, Olga R., Stevens, Robert D., Perry, Christopher G. R., Lark, Daniel S., Hui, Simon T., Szweda, Luke, Neufer, P. Darrell, Muoio, Deborah M.
Publicado em 2014

Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study

Por Salisbury-Ruf, Christi T, Bertram, Clinton C, Vergeade, Aurelia, Lark, Daniel S, Shi, Qiong, Heberling, Marlene L, Fortune, Niki L, Okoye, G Donald, Jerome, W Gray, Wells, Quinn S, Fessel, Josh, Moslehi, Javid, Chen, Heidi, Roberts, L Jackson, Boutaud, Olivier, Gamazon, Eric R, Zinkel, Sandra S
Publicado no eLife (2018)