STEP Levels Are Unchanged in Pre-Frontal Cortex and Associative Striatum in Post-Mortem Human Brain Samples from Subjects with Schizophrenia, Bipolar Disorder and Major Depressive...

Por Lanz, Thomas A., Joshi, J. Julie, Reinhart, Veronica, Johnson, Kjell, Grantham II, Lonnie E., Volfson, Dmitri
Publicado no PLoS One (2015)

3’Pool-seq: an optimized cost-efficient and scalable method of whole-transcriptome gene expression profiling

Por Sholder, Gabriel, Lanz, Thomas A., Moccia, Robert, Quan, Jie, Aparicio-Prat, Estel, Stanton, Robert, Xi, Hualin S.
Publicado no BMC Genomics (2020)

Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action

Por Lanz, Thomas A, Guilmette, Edward, Gosink, Mark M, Fischer, James E, Fitzgerald, Lawrence W, Stephenson, Diane T, Pletcher, Mathew T
Publicado em 2013

Postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus among matched tetrad...

Por Lanz, Thomas A., Reinhart, Veronica, Sheehan, Mark J., Rizzo, Stacey J. Sukoff, Bove, Susan E., James, Larry C., Volfson, Dmitri, Lewis, David A., Kleiman, Robin J.
Publicado no Transl Psychiatry (2019)

Schizophrenia-associated SLC39A8 polymorphism is a loss-of-function allele altering glutamate receptor and innate immune signaling

Por Tseng, Wei Chou, Reinhart, Veronica, Lanz, Thomas A., Weber, Mark L., Pang, Jincheng, Le, Kevin Xuong Vinh, Bell, Robert D., O’Donnell, Patricio, Buhl, Derek L.
Publicado no Transl Psychiatry (2021)

GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons

Por Garst-Orozco, Jonathan, Malik, Ruchi, Lanz, Thomas A., Weber, Mark L., Xi, Hualin, Arion, Dominique, Enwright, John F., Lewis, David A., O’Donnell, Patricio, Sohal, Vikaas S., Buhl, Derek L.
Publicado no PLoS One (2020)

Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury

Por Piro, Justin R., Suidan, Georgette L., Quan, Jie, Pi, YeQing, O’Neill, Sharon M., Ilardi, Marissa, Pozdnyakov, Nikolay, Lanz, Thomas A., Xi, Hualin, Bell, Robert D., Samad, Tarek A.
Publicado no J Neuroinflammation (2018)

MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function

Por Miller, Brooke H., Zeier, Zane, Xi, Li, Lanz, Thomas A., Deng, Shibing, Strathmann, Julia, Willoughby, David, Kenny, Paul J., Elsworth, John D., Lawrence, Matthew S., Roth, Robert H., Edbauer, Dieter, Kleiman, Robin J., Wahlestedt, Claes
Publicado em 2012

An Assessment of LRRK2 Serine 935 Phosphorylation in Human Peripheral Blood Mononuclear Cells in Idiopathic Parkinson’s Disease and G2019S LRRK2 Cohorts

Por Padmanabhan, Shalini, Lanz, Thomas A., Gorman, Donal, Wolfe, Michele, Joyce, Alison, Cabrera, Carlos, Lawrence-Henderson, Rosemary, Levers, Najah, Joshi, Neal, Ma, Thong C., Liong, Christopher, Narayan, Sushma, Alcalay, Roy N., Hutten, Samantha J., Baptista, Marco A.S., Merchant, Kalpana
Publicado no J Parkinsons Dis (2020)

A Central Role for LRRK2 in Idiopathic Parkinson Disease

Por Di Maio, Roberto, Hoffman, Eric K., Rocha, Emily M., Keeney, Matthew T., Sanders, Laurie H., De Miranda, Briana R., Zharikov, Alevtina, Van Laar, Amber, Stepan, Antonia, Lanz, Thomas A., Kofler, Julia K., Burton, Edward A., Alessi, Dario R., Hastings, Teresa G., Greenamyre, J. Timothy
Publicado no Sci Transl Med (2018)

Activated microglia cause metabolic disruptions in developmental cortical interneuron that persist in schizophrenia-patient-derived interneurons

Por Park, Gun-Hoo, Noh, Haneul, Shao, Zhicheng, Ni, Peiyan, Qin, Yiren, Liu, Dongxin, Beaudreault, Cameron P., Park, Joy S., Abani, Chiderah P., Park, James M., Le, Derek T., Gonzalez, Sasha Z., Guan, Youxin, Cohen, Bruce M., McPhie, Donna L., Coyle, Joseph T., Lanz, Thomas A., Xi, Hualin S, Yin, Changhong, Huang, Weihua, Kim, Hae-Young, Chung, Sangmi
Publicado no Nat Neurosci (2020)

Dysregulated protocadherin-pathway activity as an intrinsic defect in iPSC-derived cortical interneurons from patients with schizophrenia

Por Shao, Zhicheng, Noh, Haneul, Kim, Woong Bin, Ni, Peiyan, Nguyen, Christine, Cote, Sarah E., Noyes, Elizabeth, Zhao, Joyce, Parsons, Teagan, Park, James M., Zheng, Kelvin, Park, Joshua J., Coyle, Joseph T., Weinberger, Daniel R., Straub, Richard E., Berman, Karen F., Apud, Jose, Ongur, Dost, Cohen, Bruce M., McPhie, Donna L., Rapoport, Judith L., Perlis, Roy H., Lanz, Thomas A., Xi, Hualin Simon, Yin, Changhong, Huang, Weihua, Hirayama, Teruyoshi, Fukuda, Emi, Yagi, Takeshi, Ghosh, Sulagna, Eggan, Kevin C., Kim, Hae-Young, Eisenberg, Leonard M., Moghadam, Alexander A., Stanton, Patric K., Cho, Jun-Hyeong, Chung, Sangmi
Publicado no Nat Neurosci (2019)