Efficacy of Cyclooctadepsipeptides and Aminophenylamidines against Larval, Immature and Mature Adult Stages of a Parasitologically Characterized Trichurosis Model in Mice

por Kulke, Daniel, Krücken, Jürgen, Harder, Achim, von Samson-Himmelstjerna, Georg
Publicado 2014

Macrocyclic lactone anthelmintic-induced leukocyte binding to Dirofilaria immitis microfilariae: Influence of the drug resistance status of the parasite

por Berrafato, Tessa, Coates, Ruby, Reaves, Barbara J., Kulke, Daniel, Wolstenholme, Adrian J.
Publicado en Int J Parasitol Drugs Drug Resist (2019)

Caenorhabditis elegans in anthelmintic research – Old model, new perspectives

por Hahnel, Steffen R., Dilks, Clayton M., Heisler, Iring, Andersen, Erik C., Kulke, Daniel
Publicado en Int J Parasitol Drugs Drug Resist (2020)

Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel

por Kashyap, Sudhanva S., Verma, Saurabh, Voronin, Denis, Lustigman, Sara, Kulke, Daniel, Robertson, Alan P., Martin, Richard J.
Publicado en PLoS Pathog (2019)

Dirofilaria immitis Microfilariae and Third-Stage Larvae Induce Canine NETosis Resulting in Different Types of Neutrophil Extracellular Traps

por Muñoz-Caro, Tamara, Conejeros, Iván, Zhou, Ershun, Pikhovych, Anton, Gärtner, Ulrich, Hermosilla, Carlos, Kulke, Daniel, Taubert, Anja
Publicado en Front Immunol (2018)

Efficacy evaluation of anthelmintic products against an infection with the canine hookworm (Ancylostoma caninum) isolate Worthy 4.1F3P in dogs

por Jimenez Castro, Pablo D., Mansour, Abdelmoneim, Charles, Samuel, Hostetler, Joe, Settje, Terry, Kulke, Daniel, Kaplan, Ray M.
Publicado en Int J Parasitol Drugs Drug Resist (2020)

Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration

por Krücken, Jürgen, Holden-Dye, Lindy, Keiser, Jennifer, Prichard, Roger K., Townson, Simon, Makepeace, Benjamin L., Hübner, Marc P., Hahnel, Steffen R., Scandale, Ivan, Harder, Achim, Kulke, Daniel
Publicado en PLoS Pathog (2021)

Characterization of the Ca(2+)-Gated and Voltage-Dependent K(+)-Channel Slo-1 of Nematodes and Its Interaction with Emodepside

por Kulke, Daniel, von Samson-Himmelstjerna, Georg, Miltsch, Sandra M., Wolstenholme, Adrian J., Jex, Aaron R., Gasser, Robin B., Ballesteros, Cristina, Geary, Timothy G., Keiser, Jennifer, Townson, Simon, Harder, Achim, Krücken, Jürgen
Publicado en PLoS Negl Trop Dis (2014)

Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis

por Bah, Germanus S., Schneckener, Sebastian, Hahnel, Steffen R., Bayang, Nicolas H., Fieseler, Helena, Schmuck, Gabriele M., Krebber, Ralph, Sarr, Anouk, Terjung, Carsten, Ngangyung, Henrietta F., Ekale, David D., Mfopit, Youssouf M., Rufener, Lucien, Graham-Brown, John, Tanya, Vincent N., Glenschek-Sieberth, Martin, Kulke, Daniel, Makepeace, Benjamin L.
Publicado en PLoS Pathog (2021)