Cell cycle regulation of thymidine kinase: residues near the carboxyl terminus are essential for the specific degradation of the enzyme at mitosis.

Por Kauffman, M G, Kelly, T J
Publicado em 1991

Epidemiologic analysis of outcomes in matenal and infant health in evaluating effectiveness of three patient care teams.

Por Kauffman, M C, Cunningham, A
Publicado em 1970

Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A.

Por Virshup, D M, Kauffman, M G, Kelly, T J
Publicado em 1989

Epstein Barr Virus Associated Posttransplant Lymphoproliferative Disease After Intestinal Transplantation

Por Reyes, J., Green, M., Bueno, J., Jabbour, N., Nalesnik, M., Yunis, E., Kocoshis, S., Kauffman, M., Todo, S., Starzl, T.E.
Publicado em 1996

KPT-330 has antitumour activity against non-small cell lung cancer

Por Sun, H, Hattori, N, Chien, W, Sun, Q, Sudo, M, E-Ling, G L, Ding, L, Lim, S L, Shacham, S, Kauffman, M, Nakamaki, T, Koeffler, H P
Publicado em 2014

KPT-8602, a second-generation inhibitor of XPO1-mediated nuclear export, is well tolerated and highly active against AML blasts and leukemia-initiating cells

Por Etchin, J, Berezovskaya, A, Conway, A S, Galinsky, I A, Stone, R M, Baloglu, E, Senapedis, W, Landesman, Y, Kauffman, M, Shacham, S, Wang, J C Y, Look, A T
Publicado no Leukemia (2017)

Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276

Por Schmidt, J, Braggio, E, Kortuem, KM, Egan, JB, Zhu, YX, Xin, CS, Tiedemann, RE, Palmer, SE, Garbitt, VM, McCauley, D, Kauffman, M, Shacham, S, Chesi, M, Bergsagel, PL, Stewart, AK
Publicado em 2013

Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells

Por Etchin, J, Sun, Q, Kentsis, A, Farmer, A, Zhang, Z C, Sanda, T, Mansour, M R, Barcelo, C, McCauley, D, Kauffman, M, Shacham, S, Christie, A L, Kung, A L, Rodig, S J, Chook, Y M, Look, A T
Publicado em 2013

Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-initiating cells engrafted into immunosuppressed NSG mice

Por Etchin, J, Montero, J, Berezovskaya, A, Le, BT, Kentsis, A, Christie, AL, Conway, AS, Chen, WC, Reed, C, Mansour, MR, Ng, CEL, Adamia, S, Rodig, SJ, Galinsky, IA, Stone, RM, Klebanov, B, Landesman, Y, Kauffman, M, Shacham, S, Kung, AL, Wang, JCY, Letai, A, Look, AT
Publicado no Leukemia (2015)

CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications

Por Tai, Y-T, Landesman, Y, Acharya, C, Calle, Y, Zhong, MY, Cea, M, Tannenbaum, D, Cagnetta, A, Reagan, M, Munshi, AA, Senapedis, W, Saint-Martin, J-R, Kashyap, T, Shacham, S, Kauffman, M, Gu, Y, Wu, L, Ghobrial, I, Zhan, F, Kung, AL, Schey, SA, Richardson, P, Munshi, NC, Anderson, KC
Publicado em 2013