Activation loop phosphorylation regulates B‐Raf in vivo and transformation by B‐Raf mutants

di Köhler, Martin, Röring, Michael, Schorch, Björn, Heilmann, Katharina, Stickel, Natalie, Fiala, Gina J, Schmitt, Lisa C, Braun, Sandra, Ehrenfeld, Sophia, Uhl, Franziska M, Kaltenbacher, Thorsten, Weinberg, Florian, Herzog, Sebastian, Zeiser, Robert, Schamel, Wolfgang W, Jumaa, Hassan, Brummer, Tilman
Pubblicato in EMBO J (2015)

Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition

di Catalano, Antonella, Adlesic, Mojca, Kaltenbacher, Thorsten, Klar, Rhena F. U., Albers, Joachim, Seidel, Philipp, Brandt, Laura P., Hejhal, Tomas, Busenhart, Philipp, Röhner, Niklas, Zodel, Kyra, Fritsch, Kornelia, Wild, Peter J., Duyster, Justus, Fritsch, Ralph, Brummer, Tilman, Frew, Ian J.
Pubblicato in Cancers (Basel) (2021)

Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment

di Falcomatà, Chiara, Bärthel, Stefanie, Widholz, Sebastian A., Schneeweis, Christian, Montero, Juan José, Toska, Albulena, Mir, Jonas, Kaltenbacher, Thorsten, Heetmeyer, Jeannine, Swietlik, Jonathan J, Cheng, Jing-Yuan, Teodorescu, Bianca, Reichert, Oliver, Schmitt, Constantin, Grabichler, Kathrin, Coluccio, Andrea, Boniolo, Fabio, Veltkamp, Christian, Zukowska, Magdalena, Vargas, Angelica Arenas, Paik, Woo Hyun, Jesinghaus, Moritz, Steiger, Katja, Maresch, Roman, Öllinger, Rupert, Ammon, Tim, Baranov, Olga, Robles, Maria S., Rechenberger, Julia, Kuster, Bernhard, Meissner, Felix, Reichert, Maximilian, Flossdorf, Michael, Rad, Roland, Schmidt-Supprian, Marc, Schneider, Günter, Saur, Dieter
Pubblicato in Nat Cancer (2022)

Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

di Mueller, Sebastian, Engleitner, Thomas, Maresch, Roman, Zukowska, Magdalena, Lange, Sebastian, Kaltenbacher, Thorsten, Konukiewitz, Björn, Öllinger, Rupert, Zwiebel, Maximilian, Strong, Alex, Yen, Hsi-Yu, Banerjee, Ruby, Louzada, Sandra, Fu, Beiyuan, Seidler, Barbara, Götzfried, Juliana, Schuck, Kathleen, Hassan, Zonera, Arbeiter, Andreas, Schönhuber, Nina, Klein, Sabine, Veltkamp, Christian, Friedrich, Mathias, Rad, Lena, Barenboim, Maxim, Ziegenhain, Christoph, Hess, Julia, Dovey, Oliver M., Eser, Stefan, Parekh, Swati, Constantino-Casas, Fernando, de la Rosa, Jorge, Sierra, Marta I., Fraga, Mario, Mayerle, Julia, Klöppel, Günter, Cadiñanos, Juan, Liu, Pentao, Vassiliou, George, Weichert, Wilko, Steiger, Katja, Enard, Wolfgang, Schmid, Roland M., Yang, Fengtang, Unger, Kristian, Schneider, Günter, Varela, Ignacio, Bradley, Allan, Saur, Dieter, Rad, Roland
Pubblicato in Nature (2018)