Epigenetics and Aging: Status, Challenges, and Needs for the Future

Por Kahn, Arnold, Fraga, Mario F.
Publicado em 2009

SirT1 brings stemness closer to cancer and aging

Por Calvanese, Vincenzo, Fraga, Mario F.
Publicado em 2011

Epigenetics of Aging

Por Sierra, Marta I., Fernández, Agustín F., Fraga, Mario F.
Publicado no Curr Genomics (2015)

The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties

Por Fraga, Mario F., Ballestar, Esteban, Montoya, Guillermo, Taysavang, Panya, Wade, Paul A., Esteller, Manel
Publicado em 2003

Role of DNA methylation in the regulation of the RANKL-OPG system in human bone

Por Delgado-Calle, Jesús, Sañudo, Carolina, Fernández, Agustín F., García-Renedo, Raúl, Fraga, Mario F., Riancho, José A.
Publicado em 2012

Aging Genetics and Aging

Por Rodríguez-Rodero, Sandra, Fernández-Morera, Juan Luis, Menéndez-Torre, Edelmiro, Calvanese, Vincenzo, Fernández, Agustín F., Fraga, Mario F.
Publicado em 2011

DNA methylation patterns in newborns exposed to tobacco in utero

Por Ivorra, Carmen, Fraga, Mario F, Bayón, Gustavo F, Fernández, Agustín F, Garcia-Vicent, Consuelo, Chaves, F Javier, Redon, Josep, Lurbe, Empar
Publicado no J Transl Med (2015)

Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma

Por Berdasco, María, Ropero, Santiago, Setien, Fernando, Fraga, Mario F., Lapunzina, Pablo, Losson, Régine, Alaminos, Miguel, Cheung, Nai-Kong, Rahman, Nazneen, Esteller, Manel
Publicado em 2009

Longitudinal study of DNA methylation during the first 5 years of life

Por Urdinguio, Rocio G., Torró, María Isabel, Bayón, Gustavo F., Álvarez-Pitti, Julio, Fernández, Agustín F., Redon, Pau, Fraga, Mario F., Lurbe, Empar
Publicado no J Transl Med (2016)

Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer

Por Ballestar, Esteban, Paz, Maria F., Valle, Laura, Wei, Susan, Fraga, Mario F., Espada, Jesus, Cruz Cigudosa, Juan, Huang, Tim Hui-Ming, Esteller, Manel
Publicado em 2003

HERG1A potassium channel is the predominant isoform in head and neck squamous cell carcinomas: evidence for regulation by epigenetic mechanisms

Por Menéndez, Sofía T., Villaronga, M. Ángeles, Rodrigo, Juan P., Álvarez-Teijeiro, Saúl, Urdinguio, Rocío G., Fraga, Mario F., Suárez, Carlos, García-Pedrero, Juana M.
Publicado no Sci Rep (2016)

The loss of NKX3.1 expression in testicular – and prostate – cancers is not caused by promoter hypermethylation

Por Lind, Guro E, Skotheim, Rolf I, Fraga, Mario F, Abeler, Vera M, Henrique, Rui, Saatcioglu, Fahri, Esteller, Manel, Teixeira, Manuel R, Lothe, Ragnhild A
Publicado em 2005

DNA methylation-mediated silencing of PU.1 in leukemia cells resistant to cell differentiation

Por Fernández-Nestosa, María José, Monturus, Estefanía, Sánchez, Zunilda, Torres, Francisco S, Fernández, Agustín F, Fraga, Mario F, Hernández, Pablo, Schvartzman, Jorge B, Krimer, Dora B
Publicado em 2013

Genome-wide DNA methylation changes with age in disease-free human skeletal muscle

Por Zykovich, Artem, Hubbard, Alan, Flynn, James M, Tarnopolsky, Mark, Fraga, Mario F, Kerksick, Chad, Ogborn, Dan, MacNeil, Lauren, Mooney, Sean D, Melov, Simon
Publicado em 2014

Oncometabolic Nuclear Reprogramming of Cancer Stemness

Por Menendez, Javier A., Corominas-Faja, Bruna, Cuyàs, Elisabet, García, María G., Fernández-Arroyo, Salvador, Fernández, Agustín F., Joven, Jorge, Fraga, Mario F., Alarcón, Tomás
Publicado no Stem Cell Reports (2016)

DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster

Por Zagorac, Sladjana, Alcala, Sonia, Bayon, Gustavo Fernandez, Kheir, Tony Bou, Schoenhals, Matthieu, González-Neira, Anna, Fraga, Mario Fernandez, Aicher, Alexandra, Heeschen, Christopher, Sainz, Bruno
Publicado no Cancer Res (2016)

Molecular Analysis of a Multistep Lung Cancer Model Induced by Chronic Inflammation Reveals Epigenetic Regulation of p16 and Activation of the DNA Damage Response Pathway

Por Blanco, David, Vicent, Silvestre, Fraga, Mario F, Fernandez-Garcia, Ignacio, Freire, Javier, Lujambio, Amaia, Esteller, Manel, Ortiz-de-Solorzano, Carlos, Pio, Ruben, Lecanda, Fernando, Montuenga, Luis M
Publicado em 2007

The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA

Por López de Silanes, Isabel, Gorospe, Myriam, Taniguchi, Hiroaki, Abdelmohsen, Kotb, Srikantan, Subramanya, Alaminos, Miguel, Berdasco, María, Urdinguio, Rocío G., Fraga, Mario F., Jacinto, Filipe V., Esteller, Manel
Publicado em 2009

Epigenetic Mechanisms Regulate MHC and Antigen Processing Molecules in Human Embryonic and Induced Pluripotent Stem Cells

Por Suárez-Álvarez, Beatriz, Rodriguez, Ramón M., Calvanese, Vincenzo, Blanco-Gelaz, Miguel A., Suhr, Steve T., Ortega, Francisco, Otero, Jesus, Cibelli, Jose B., Moore, Harry, Fraga, Mario F., López-Larrea, Carlos
Publicado em 2010

DNA Methylation Dynamics in Blood after Hematopoietic Cell Transplant

Por Rodriguez, Ramon M., Suarez-Alvarez, Beatriz, Salvanés, Rubén, Muro, Manuel, Martínez-Camblor, Pablo, Colado, Enrique, Sánchez, Miguel Alcoceba, Díaz, Marcos González, Fernandez, Agustin F., Fraga, Mario F., Lopez-Larrea, Carlos
Publicado em 2013