Identification of a germline F692L drug resistance variant in cis with Flt3-internal tandem duplication in knock-in mice

Por Dovey, Oliver M., Chen, Bin, Mupo, Annalisa, Friedrich, Mathias, Grove, Carolyn S., Cooper, Jonathan L., Lee, Benjamin, Varela, Ignacio, Huang, Yue, Vassiliou, George S.
Publicado no Haematologica (2016)

Enhancing the genome editing toolbox: genome wide CRISPR arrayed libraries

Por Metzakopian, Emmanouil, Strong, Alex, Iyer, Vivek, Hodgkins, Alex, Tzelepis, Konstantinos, Antunes, Liliana, Friedrich, Mathias J, Kang, Qiaohua, Davidson, Teresa, Lamberth, Jacob, Hoffmann, Christina, Davis, Gregory D., Vassiliou, George S., Skarnes, William C., Bradley, Allan
Publicado no Sci Rep (2017)

A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes

Por de la Rosa, Jorge, Weber, Julia, Friedrich, Mathias Josef, Li, Yilong, Rad, Lena, Ponstingl, Hannes, Liang, Qi, de Quirós, Sandra Bernaldo, Noorani, Imran, Metzakopian, Emmanouil, Strong, Alexander, Li, Meng Amy, Astudillo, Aurora, Fernández-García, María Teresa, Fernández-García, María Soledad, Hoffman, Gary J., Fuente, Rocío, Vassiliou, George S., Rad, Roland, López-Otín, Carlos, Bradley, Allan, Cadiñanos, Juan
Publicado no Nat Genet (2017)

Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice

Por Maresch, Roman, Mueller, Sebastian, Veltkamp, Christian, Öllinger, Rupert, Friedrich, Mathias, Heid, Irina, Steiger, Katja, Weber, Julia, Engleitner, Thomas, Barenboim, Maxim, Klein, Sabine, Louzada, Sandra, Banerjee, Ruby, Strong, Alexander, Stauber, Teresa, Gross, Nina, Geumann, Ulf, Lange, Sebastian, Ringelhan, Marc, Varela, Ignacio, Unger, Kristian, Yang, Fengtang, Schmid, Roland M., Vassiliou, George S., Braren, Rickmer, Schneider, Günter, Heikenwalder, Mathias, Bradley, Allan, Saur, Dieter, Rad, Roland
Publicado no Nat Commun (2016)

CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice

Por Weber, Julia, Öllinger, Rupert, Friedrich, Mathias, Ehmer, Ursula, Barenboim, Maxim, Steiger, Katja, Heid, Irina, Mueller, Sebastian, Maresch, Roman, Engleitner, Thomas, Gross, Nina, Geumann, Ulf, Fu, Beiyuan, Segler, Angela, Yuan, Detian, Lange, Sebastian, Strong, Alexander, de la Rosa, Jorge, Esposito, Irene, Liu, Pentao, Cadiñanos, Juan, Vassiliou, George S., Schmid, Roland M., Schneider, Günter, Unger, Kristian, Yang, Fengtang, Braren, Rickmer, Heikenwälder, Mathias, Varela, Ignacio, Saur, Dieter, Bradley, Allan, Rad, Roland
Publicado no Proc Natl Acad Sci U S A (2015)