Pharmacokinetics and Pharmacodynamics of Darunavir and Etravirine in HIV-1–Infected, Treatment-Experienced Patients in the Gender, Race, and Clinical Experience (GRACE) Trial

Por Kakuda, Thomas, Sekar, Vanitha, Vis, Peter, Coate, Bruce, Ryan, Robert, Anderson, David, De La Rosa, Guy, Mrus, Joseph
Publicado em 2012

Single‐ and multiple‐dose pharmacokinetics and safety of pimodivir, a novel, non‐nucleoside polymerase basic protein 2 subunit inhibitor of the influenza A virus polymerase complex...

Por Deleu, Sofie, Kakuda, Thomas N., Spittaels, Kurt, Vercauteren, Jurgen J., Hillewaert, Vera, Lwin, Amy, Leopold, Lorant, Hoetelmans, Richard M. W.
Publicado no Br J Clin Pharmacol (2018)

A pharmacokinetic study of etravirine (TMC125) co-administered with ranitidine and omeprazole in HIV–negative volunteers

Por Schöller-Gyüre, Monika, Kakuda, Thomas N, De Smedt, Goedele, Vanaken, Hilde, Bouche, Marie-Paule, Peeters, Monika, Woodfall, Brian, Hoetelmans, Richard M W
Publicado em 2008

Pharmacokinetics of Etravirine Combined with Atazanavir/Ritonavir and a Nucleoside Reverse Transcriptase Inhibitor in Antiretroviral Treatment-Experienced, HIV-1-Infected Patients

Por Orrell, Catherine, Felizarta, Franco, Nell, André, Kakuda, Thomas N., Lavreys, Ludo, Nijs, Steven, Tambuyzer, Lotke, Van Solingen-Ristea, Rodica, Tomaka, Frank L.
Publicado no AIDS Res Treat (2015)

Pharmacological Basis for Concentration-Controlled Therapy with Zidovudine, Lamivudine, and Indinavir

Por Kakuda, Thomas N., Page, Linda M., Anderson, Peter L., Henry, Keith, Schacker, Timothy W., Rhame, Frank S., Acosta, Edward P., Brundage, Richard C., Fletcher, Courtney V.
Publicado em 2001

Minimal Pharmacokinetic Interaction between the Human Immunodeficiency Virus Nonnucleoside Reverse Transcriptase Inhibitor Etravirine and the Integrase Inhibitor Raltegravir in Hea...

Por Anderson, Matt S., Kakuda, Thomas N., Hanley, William, Miller, Jutta, Kost, James T., Stoltz, Randall, Wenning, Larissa A., Stone, Julie A., Hoetelmans, Richard M. W., Wagner, John A., Iwamoto, Marian
Publicado em 2008

Pharmacokinetic Interactions of Maraviroc with Darunavir-Ritonavir, Etravirine, and Etravirine-Darunavir-Ritonavir in Healthy Volunteers: Results of Two Drug Interaction Trials

Por Kakuda, Thomas N., Abel, Samantha, Davis, John, Hamlin, Julia, Schöller-Gyüre, Monika, Mack, Rebecca, Ndongo, Noella, Petit, Wendy, Ridgway, Caroline, Sekar, Vanitha, Tweedy, Sarah, Hoetelmans, Richard M. W.
Publicado em 2011

Phase IIIb, open-label single-arm trial of darunavir/cobicistat (DRV/COBI): Week 48 subgroup analysis of HIV-1-infected treatment-nave adults

Por Tashima, Karen, Crofoot, Gordon, Tomaka, Frank L, Kakuda, Thomas N, Brochot, Anne, Vanveggel, Simon, Opsomer, Magda, Garner, William, Margot, Nicolas, Custodio, Joseph M, Fordyce, Marshall W, Szwarcberg, Javier
Publicado no J Int AIDS Soc (2014)

Cobicistat-boosted darunavir in HIV-1-infected adults: week 48 results of a Phase IIIb, open-label single-arm trial

Por Tashima, Karen, Crofoot, Gordon, Tomaka, Frank L, Kakuda, Thomas N, Brochot, Anne, Van de Casteele, Tom, Opsomer, Magda, Garner, William, Margot, Nicolas, Custodio, Joseph M, Fordyce, Marshall W, Szwarcberg, Javier
Publicado no AIDS Res Ther (2014)

Pharmacokinetics, safety, and tolerability of the 2‐ and 3‐direct‐acting antiviral combination of AL‐335, odalasvir, and simeprevir in healthy subjects

Por Kakuda, Thomas N., McClure, Matthew W., Westland, Christopher, Vuong, Jennifer, Homery, Marie‐Claude, Poizat, Gwendoline, Viguerie, Laure, Denot, Caroline, Patat, Alain, Zhang, Qingling, Hui, James, Apelian, David, Smith, David B., Chanda, Sushmita M., Fry, John
Publicado no Pharmacol Res Perspect (2018)

Safety, tolerability, and pharmacokinetics of AL-335 in healthy volunteers and hepatitis C virus-infected subjects

Por McClure, Matthew W., Berliba, Elina, Tsertsvadze, Tengiz, Streinu-Cercel, Adrian, Vijgen, Leen, Astruc, Béatrice, Patat, Alain, Westland, Christopher, Chanda, Sushmita, Zhang, Qingling, Kakuda, Thomas N., Vuong, Jennifer, Khorlin, Nick, Beigelman, Leonid, Blatt, Lawrence M., Fry, John
Publicado no PLoS One (2018)

Efficacy, safety and pharmacokinetics of simeprevir and TMC647055/ritonavir with or without ribavirin and JNJ-56914845 in HCV genotype 1 infection

Por Bourgeois, Stefan, Van Vlierberghe, Hans, Moreno, Christophe, Orlent, Hans, Nevens, Frederik, Arastéh, Keikawus, Horsmans, Yves, Schattenberg, Jörn M., Buggisch, Peter, Francque, Sven, Vijgen, Leen, Kakuda, Thomas N., Hoeben, Eva, Luo, Donghan, Vandebosch, An, Jacquemyn, Bert, Van Remoortere, Pieter, Verloes, René
Publicado no BMC Gastroenterol (2017)