Idiosyncratic drug reactions: a mechanistic evaluation of risk factors.

Por Park, B K, Pirmohamed, M, Kitteringham, N R
Publicado em 1992

Detection of autoantibodies directed against human hepatic endoplasmic reticulum in sera from patients with halothane-associated hepatitis.

Por Kitteringham, N R, Kenna, J G, Park, B K
Publicado em 1995

Structural requirements for bioactivation of anticonvulsants to cytotoxic metabolites in vitro.

Por Riley, R J, Kitteringham, N R, Park, B K
Publicado em 1989

The effect of chlorpromazine, metyrapone, imipramine and SKF 525-A on the hepatic first pass elimination of propranolol in the pithed rat.

Por Barber, H. E., Kitteringham, N. R., Petrie, J. C.
Publicado em 1982

Relevance of induction of human drug-metabolizing enzymes: pharmacological and toxicological implications

Por PARK, B. K., KITTERINGHAM, N. R., PIRMOHAMED, M., TUCKER, G. T.
Publicado em 1996

Inhibition of caffeine metabolism by ciprofloxacin in children with cystic fibrosis as measured by the caffeine breath test.

Por Parker, A C, Preston, T, Heaf, D, Kitteringham, N R, Choonara, I
Publicado em 1994

Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepine hypersensitivity.

Por Pirmohamed, M, Kitteringham, N R, Breckenridge, A M, Park, B K
Publicado em 1992

A stereochemical investigation of the cytotoxicity of mianserin metabolites in vitro.

Por Riley, R J, Lambert, C, Kitteringham, N R, Park, B K
Publicado em 1989

A comparative study of the formation of chemically reactive drug metabolites by human liver microsomes.

Por Kitteringham, N R, Lambert, C, Maggs, J L, Colbert, J, Park, B K
Publicado em 1988

Glutathione S-transferase mu genotype (GSTM1*0) in Alzheimer's patients with tacrine transaminitis.

Por Green, V J, Pirmohamed, M, Kitteringham, N R, Knapp, M J, Park, B K
Publicado em 1995

Bioactivation of dapsone to a cytotoxic metabolite: in vitro use of a novel two compartment system which contains human tissues.

Por Riley, R J, Roberts, P, Coleman, M D, Kitteringham, N R, Park, B K
Publicado em 1990

An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin.

Por Riley, R J, Maggs, J L, Lambert, C, Kitteringham, N R, Park, B K
Publicado em 1988

Lymphocyte microsomal epoxide hydrolase in patients on carbamazepine therapy.

Por Pirmohamed, M, Allott, R, Green, V J, Kitteringham, N R, Chadwick, D, Park, B K
Publicado em 1994

An investigation of the interaction between halofantrine, CYP2D6 and CYP3A4: studies with human liver microsomes and heterologous enzyme expression systems.

Por Halliday, R C, Jones, B C, Smith, D A, Kitteringham, N R, Park, B K
Publicado em 1995

Interaction between the β-adrenoceptor blockers metoprolol and atenolol with amitriptyline and their effects on oxidative liver metabolism

Por Kirch, W., Spahn, H., Kitteringham, N. R., Hutt, H. J., Mutschler, E., Ohnhaus, E. E.
Publicado em 1984

Pharmacokinetic and pharmacodynamic interactions between phenprocoumon and atenolol or metoprolol

Por Spahn, H., Kirch, W., Mutschler, E., Ohnhaus, E. E., Kitteringham, N. R., Lögering, H. J., Paar, D.
Publicado em 1984

α(1)-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice

Por Randle, L E, Sathish, J G, Kitteringham, N R, Macdonald, I, Williams, D P, Park, B K
Publicado em 2008

iTRAQ reveals candidate pancreatic cancer serum biomarkers: influence of obstructive jaundice on their performance

Por Tonack, S, Jenkinson, C, Cox, T, Elliott, V, Jenkins, R E, Kitteringham, N R, Greenhalf, W, Shaw, V, Michalski, C W, Friess, H, Neoptolemos, J P, Costello, E
Publicado em 2013

Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics.

Por Forrester, L M, Henderson, C J, Glancey, M J, Back, D J, Park, B K, Ball, S E, Kitteringham, N R, McLaren, A W, Miles, J S, Skett, P
Publicado em 1992

Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome

Por Eakins, R., Walsh, J., Randle, L., Jenkins, R. E., Schuppe-Koistinen, I., Rowe, C., Starkey Lewis, P., Vasieva, O., Prats, N., Brillant, N., Auli, M., Bayliss, M., Webb, S., Rees, J. A., Kitteringham, N. R., Goldring, C. E., Park, B. K.
Publicado no Sci Rep (2015)