Expression, purification, crystallization and X-ray data collection for RAS and its mutants

由 Johnson, Christian W., Buhrman, Greg, Ting, Pamela Y., Colicelli, John, Mattos, Carla
發表在 Data Brief (2015)

The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects

由 Johnson, Christian W., Reid, Derion, Parker, Jillian A., Salter, Shores, Knihtila, Ryan, Kuzmic, Petr, Mattos, Carla
發表在 J Biol Chem (2017)

Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding

由 Ting, Pamela Y., Johnson, Christian W., Fang, Cong, Cao, Xiaoqing, Graeber, Thomas G., Mattos, Carla, Colicelli, John
發表在 FASEB J (2015)

Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D

由 Johnson, Christian W., Lin, Yi-Jang, Reid, Derion, Parker, Jillian, Pavlopoulos, Spiro, Dischinger, Patrick, Graveel, Carrie, Aguirre, Andrew J., Steensma, Matthew, Haigis, Kevin M., Mattos, Carla
發表在 Cell Rep (2019)

Tissue-specific oncogenic activity of K-Ras(A146T)

由 Poulin, Emily J., Bera, Asim K., Lu, Jia, Lin, Yi-Jang, Strasser, Samantha Dale, Paulo, Joao A., Huang, Tannie Q., Morales, Carolina, Yan, Wei, Cook, Joshua, Nowak, Jonathan A., Brubaker, Douglas K., Joughin, Brian A., Johnson, Christian W., DeStefanis, Rebecca A., Ghazi, Phaedra C., Gondi, Sudershan, Wales, Thomas E., Iacob, Roxana E., Bogdanova, Lana, Gierut, Jessica J., Li, Yina, Engen, John R., Perez-Mancera, Pedro A., Braun, Benjamin S., Gygi, Steven P., Lauffenburger, Douglas A., Westover, Kenneth D., Haigis, Kevin M.
發表在 Cancer Discov (2019)