Expression, purification, crystallization and X-ray data collection for RAS and its mutants

door Johnson, Christian W., Buhrman, Greg, Ting, Pamela Y., Colicelli, John, Mattos, Carla
Gepubliceerd in Data Brief (2015)

The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects

door Johnson, Christian W., Reid, Derion, Parker, Jillian A., Salter, Shores, Knihtila, Ryan, Kuzmic, Petr, Mattos, Carla
Gepubliceerd in J Biol Chem (2017)

Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding

door Ting, Pamela Y., Johnson, Christian W., Fang, Cong, Cao, Xiaoqing, Graeber, Thomas G., Mattos, Carla, Colicelli, John
Gepubliceerd in FASEB J (2015)

Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D

door Johnson, Christian W., Lin, Yi-Jang, Reid, Derion, Parker, Jillian, Pavlopoulos, Spiro, Dischinger, Patrick, Graveel, Carrie, Aguirre, Andrew J., Steensma, Matthew, Haigis, Kevin M., Mattos, Carla
Gepubliceerd in Cell Rep (2019)

Tissue-specific oncogenic activity of K-Ras(A146T)

door Poulin, Emily J., Bera, Asim K., Lu, Jia, Lin, Yi-Jang, Strasser, Samantha Dale, Paulo, Joao A., Huang, Tannie Q., Morales, Carolina, Yan, Wei, Cook, Joshua, Nowak, Jonathan A., Brubaker, Douglas K., Joughin, Brian A., Johnson, Christian W., DeStefanis, Rebecca A., Ghazi, Phaedra C., Gondi, Sudershan, Wales, Thomas E., Iacob, Roxana E., Bogdanova, Lana, Gierut, Jessica J., Li, Yina, Engen, John R., Perez-Mancera, Pedro A., Braun, Benjamin S., Gygi, Steven P., Lauffenburger, Douglas A., Westover, Kenneth D., Haigis, Kevin M.
Gepubliceerd in Cancer Discov (2019)