Expression, purification, crystallization and X-ray data collection for RAS and its mutants

por Johnson, Christian W., Buhrman, Greg, Ting, Pamela Y., Colicelli, John, Mattos, Carla
Publicado en Data Brief (2015)

The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects

por Johnson, Christian W., Reid, Derion, Parker, Jillian A., Salter, Shores, Knihtila, Ryan, Kuzmic, Petr, Mattos, Carla
Publicado en J Biol Chem (2017)

Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding

por Ting, Pamela Y., Johnson, Christian W., Fang, Cong, Cao, Xiaoqing, Graeber, Thomas G., Mattos, Carla, Colicelli, John
Publicado en FASEB J (2015)

Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D

por Johnson, Christian W., Lin, Yi-Jang, Reid, Derion, Parker, Jillian, Pavlopoulos, Spiro, Dischinger, Patrick, Graveel, Carrie, Aguirre, Andrew J., Steensma, Matthew, Haigis, Kevin M., Mattos, Carla
Publicado en Cell Rep (2019)

Tissue-specific oncogenic activity of K-Ras(A146T)

por Poulin, Emily J., Bera, Asim K., Lu, Jia, Lin, Yi-Jang, Strasser, Samantha Dale, Paulo, Joao A., Huang, Tannie Q., Morales, Carolina, Yan, Wei, Cook, Joshua, Nowak, Jonathan A., Brubaker, Douglas K., Joughin, Brian A., Johnson, Christian W., DeStefanis, Rebecca A., Ghazi, Phaedra C., Gondi, Sudershan, Wales, Thomas E., Iacob, Roxana E., Bogdanova, Lana, Gierut, Jessica J., Li, Yina, Engen, John R., Perez-Mancera, Pedro A., Braun, Benjamin S., Gygi, Steven P., Lauffenburger, Douglas A., Westover, Kenneth D., Haigis, Kevin M.
Publicado en Cancer Discov (2019)