Expression, purification, crystallization and X-ray data collection for RAS and its mutants

le Johnson, Christian W., Buhrman, Greg, Ting, Pamela Y., Colicelli, John, Mattos, Carla
Foilsithe in Data Brief (2015)

The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects

le Johnson, Christian W., Reid, Derion, Parker, Jillian A., Salter, Shores, Knihtila, Ryan, Kuzmic, Petr, Mattos, Carla
Foilsithe in J Biol Chem (2017)

Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding

le Ting, Pamela Y., Johnson, Christian W., Fang, Cong, Cao, Xiaoqing, Graeber, Thomas G., Mattos, Carla, Colicelli, John
Foilsithe in FASEB J (2015)

Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D

le Johnson, Christian W., Lin, Yi-Jang, Reid, Derion, Parker, Jillian, Pavlopoulos, Spiro, Dischinger, Patrick, Graveel, Carrie, Aguirre, Andrew J., Steensma, Matthew, Haigis, Kevin M., Mattos, Carla
Foilsithe in Cell Rep (2019)

Tissue-specific oncogenic activity of K-Ras(A146T)

le Poulin, Emily J., Bera, Asim K., Lu, Jia, Lin, Yi-Jang, Strasser, Samantha Dale, Paulo, Joao A., Huang, Tannie Q., Morales, Carolina, Yan, Wei, Cook, Joshua, Nowak, Jonathan A., Brubaker, Douglas K., Joughin, Brian A., Johnson, Christian W., DeStefanis, Rebecca A., Ghazi, Phaedra C., Gondi, Sudershan, Wales, Thomas E., Iacob, Roxana E., Bogdanova, Lana, Gierut, Jessica J., Li, Yina, Engen, John R., Perez-Mancera, Pedro A., Braun, Benjamin S., Gygi, Steven P., Lauffenburger, Douglas A., Westover, Kenneth D., Haigis, Kevin M.
Foilsithe in Cancer Discov (2019)