ER-associated degradation regulates Alzheimer’s amyloid pathology and memory function by modulating γ-secretase activity

Yazar: Zhu, Bing, Jiang, LuLin, Huang, Timothy, Zhao, Yingjun, Liu, Tongfei, Zhong, Yongwang, Li, Xiaoguang, Campos, Alexandre, Pomeroy, Kenneth, Masliah, Eliezer, Zhang, Dongxian, Xu, Huaxi
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Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at APOE

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Reduced C9ORF72 function exacerbates gain-of-toxicity from ALS/FTD-causing repeat expansion in C9orf72

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