From Molecule to Patient: A Biotech Perspective

Por Langer, Robert, Jaklenec, Ana, Traverso, Giovanni, Hartman, Daniel
Publicado no Clin Pharmacol Ther (2019)

mRNA vaccine delivery using lipid nanoparticles

Por Reichmuth, Andreas M, Oberli, Matthias A, Jaklenec, Ana, Langer, Robert, Blankschtein, Daniel
Publicado no Ther Deliv (2016)

Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome

Por Anselmo, Aaron C., McHugh, Kevin J., Webster, Jamie, Langer, Robert, Jaklenec, Ana
Publicado no Adv Mater (2016)

Magnetic multivalent trehalose glycopolymer nanoparticles for the detection of mycobacteria

Por Chen, Xuan, Wu, Bin, Jayawardana, Kalana W., Hao, Nanjing, Jayawardena, H. Surangi N., Langer, Robert, Jaklenec, Ana, Yan, Mingdi
Publicado no Adv Healthc Mater (2016)

Immunogenicity of pulsatile-release PLGA microspheres for single-injection vaccination

Por Guarecuco, Rohiverth, Lu, Jennifer, McHugh, Kevin J., Norman, James J., Thapa, Lavanya S., Lydon, Emily, Langer, Robert, Jaklenec, Ana
Publicado no Vaccine (2018)

Thermostabilization of inactivated polio vaccine in PLGA-based microspheres for pulsatile release

Por Tzeng, Stephany Y., Guarecuco, Rohiverth, McHugh, Kevin J., Rose, Sviatlana, Rosenberg, Evan M., Zeng, Yingying, Langer, Robert, Jaklenec, Ana
Publicado no J Control Release (2016)

Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response

Por Tzeng, Stephany Y., McHugh, Kevin J., Behrens, Adam M., Rose, Sviatlana, Sugarman, James L., Ferber, Shiran, Langer, Robert, Jaklenec, Ana
Publicado no Proc Natl Acad Sci U S A (2018)

Modeling, design, and machine learning-based framework for optimal injectability of microparticle-based drug formulations

Por Sarmadi, Morteza, Behrens, Adam M., McHugh, Kevin J., Contreras, Hannah T. M., Tochka, Zachary L., Lu, Xueguang, Langer, Robert, Jaklenec, Ana
Publicado no Sci Adv (2020)

Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy

Por Oberli, Matthias A., Reichmuth, Andreas M., Dorkin, J. Robert, Mitchell, Michael J., Fenton, Owen S., Jaklenec, Ana, Anderson, Daniel G., Langer, Robert, Blankschtein, Daniel
Publicado no Nano Lett (2016)

Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse

Por Kauffman, Kevin J., Oberli, Matthias A., Dorkin, J. Robert, Hurtado, Juan E., Kaczmarek, James C., Bhadani, Shivani, Wyckoff, Jeff, Langer, Robert, Jaklenec, Ana, Anderson, Daniel G.
Publicado no Mol Ther Nucleic Acids (2017)

Chiral Effects on Supraparticles for Controllable Nanomedicine

Por Yeom, Jihyeon, Guimaraes, Pedro P. G., Ahn, Hyo Min, Jung, BoKyeong, Hu, Quanyin, McHugh, Kevin, Mitchell, Michael J., Yun, Chae-Ok, Langer, Robert, Jaklenec, Ana
Publicado no Adv Mater (2019)

Ultrasound-Mediated Delivery of RNA to Colonic Mucosa of Live Mice

Por Schoellhammer, Carl M., Lauwers, Gregory Y., Goettel, Jeremy A., Oberli, Matthias A., Cleveland, Cody, Park, June Y., Minahan, Daniel, Chen, Yiyun, Anderson, Daniel G., Jaklenec, Ana, Snapper, Scott B., Langer, Robert, Traverso, Giovanni
Publicado no Gastroenterology (2017)

Fabrication of fillable microparticles and other complex 3D microstructures

Por McHugh, Kevin J., Nguyen, Thanh D., Linehan, Allison R., Yang, David, Behrens, Adam M., Rose, Sviatlana, Tochka, Zachary L., Tzeng, Stephany Y., Norman, James J., Anselmo, Aaron C., Xu, Xian, Tomasic, Stephanie, Taylor, Matthew A., Lu, Jennifer, Guarecuco, Rohiverth, Langer, Robert, Jaklenec, Ana
Publicado no Science (2017)

Biocompatible near-infrared quantum dots delivered to the skin by microneedle patches record vaccination

Por McHugh, Kevin J., Jing, Lihong, Severt, Sean Y., Cruz, Mache, Sarmadi, Morteza, Jayawardena, Hapuarachchige Surangi N., Perkinson, Collin F., Larusson, Fridrik, Rose, Sviatlana, Tomasic, Stephanie, Graf, Tyler, Tzeng, Stephany Y., Sugarman, James L., Vlasic, Daniel, Peters, Matthew, Peterson, Nels, Wood, Lowell, Tang, Wen, Yeom, Jihyeon, Collins, Joe, Welkhoff, Philip A., Karchin, Ari, Tse, Megan, Gao, Mingyuan, Bawendi, Moungi G., Langer, Robert, Jaklenec, Ana
Publicado no Sci Transl Med (2019)