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Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response

Vaccination in the developing world is hampered by limited patient access, which prevents individuals from receiving the multiple injections necessary for protective immunity. Here, we developed an injectable microparticle formulation of the inactivated polio vaccine (IPV) that releases multiple pul...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Tzeng, Stephany Y., McHugh, Kevin J., Behrens, Adam M., Rose, Sviatlana, Sugarman, James L., Ferber, Shiran, Langer, Robert, Jaklenec, Ana
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003376/
https://ncbi.nlm.nih.gov/pubmed/29784798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720970115
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